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EVidence of tolerance Multiple sclerosis (MS) is an autoimmune disorder characterized by neuroinflammation and demyelination. Administration of myelin-specific self-antigens to induce tolerance has been shown
Immunotherapy for stomach cancer may work better if the therapy is delivered earlier in the course of disease and in combination with standard chemotherapy, a
Physicians and researchers have had questionable success treating patients with severe COVID-19 with either antibody-based drugs or convalescent plasma. Neither of those strategies is a cell-based therapy, and,
Researchers used gene therapy to regenerate damaged axons in the eye, in a discovery that could aid the development of new treatments for glaucoma, one
Highlights •Predicting triplet stimuli effects in vitro using coculture data from singles and pairs •Singles and pairs dictate the information signaled by triplets in mouse and human DCs
Abstract Cells rely upon producing enzymes at precise rates and stoichiometry for maximizing functionalities. The reasons for this optimal control are unknown, primarily because of
Researchers in Korea say they have developed an anticancer drug that could potentially prevent drug resistance. The scientists, from the Korea Institute of Science and
Highlights •NSP16 binds mRNA recognition domains of U1/U2 snRNAs and disrupts mRNA splicing •NSP1 binds in the mRNA entry channel of the ribosome to disrupt
Highlights •A new probe, PM-PBB3, captures pathological tau deposits in vivo with high contrast •PM-PBB3 allows an individual-based identification of AD and non-AD tauopathies •Autopsy assays of PET-scanned