Highlights Summary The “inactive” X chromosome (Xi) has been assumed to have little impact, in trans, on the “active” X (Xa). To test this, we quantified Xi and
Cancer is driven by multiple genetic alterations, from mutations to aneuploidy. Aneuploidy is the presence of an abnormal number of chromosomes in cancer cells. Although
Female of most mammalian species are fertile throughout their adult life. But humans are different, says University of Copenhagen molecular geneticist Eva Hoffmann. A woman’s
To date, most cases of uniparental disomy—having two copies of a chromosome from either mom or dad, rather than one from each—have been identified in
In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among
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