Abstract TARM1 is a member of the leukocyte immunoglobulin-like receptor family and stimulates macrophages and neutrophils in vitro by associating with FcRγ. However, the function
rthritis affects almost 2% of the world’s population, or some 150 million people, and currently, there is no completely effective treatment for this chronic disease.
Immune cells called macrophages commonly function as scavenger-like (phagocytic) cells that ingest and remove damaged cells. Writing in Nature, Culemann et al.1 report that the
Fibroblasts are a type of cell found in all tissues of the body. They help to maintain the structural integrity of connective tissues by secreting
What is a best-selling drug worth? In 2013, at least, it came down to at least $3 billion in annual sales—triple the $1 billion benchmark
In the movie The Big Sick, based on real events that happened to its two Academy Award-nominated scriptwriters, the character Emily falls gravely ill and
Epigenetic abnormalities are part of the pathogenetic alterations involved in the development of rheumatic disorders. In this context, the main musculoskeletal cell lineages, which are
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