Highlights Summary Many, if not all, bacteria use quorum sensing (QS) to control collective behaviors, and more recently, QS has also been discovered in bacteriophages
Abstract Despite recognition of the immediate impact of infections caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales (ESBL-PE) on human health, essential aspects of their molecular epidemiology
Abstract Bacteriophages are ubiquitous viral predators that have primarily been studied using fast-growing laboratory cultures of their bacterial hosts. However, microbial life in nature is
Significance The obligate intracellular bacterial pathogen, Coxiella burnetii, is the causative agent of the zoonotic infection termed Q fever. Agricultural outbreaks are an increasingly significant economic
Abstract Escherichia coli is a leading cause of invasive bacterial infections in humans. Capsule polysaccharide has an important role in bacterial pathogenesis, and the K1 capsule
Abstract Antibiotic resistance is a pressing healthcare challenge and is mediated by various mechanisms, including the active export of drugs via multidrug efflux systems, which
Highlights Summary Ideal therapies for regenerative medicine or healthy aging require healthy organ growth and rejuvenation, but no organ-level approach is currently available. Using Mycobacterium leprae (ML)
Abstract Genomic studies and experiments with permeability-deficient strains have revealed a variety of biological targets that can be engaged to kill Gram-negative bacteria. However, the
Abstract Membrane protein efflux pumps confer antibiotic resistance by extruding structurally distinct compounds and lowering their intracellular concentration. Yet, there are no clinically approved drugs
The emergence and global dissemination of the mobile colistin resistance (mcr) genes have threatened the use of colistin (polymyxin E), a last-resort antibiotic, in the
New research has discovered that common artificial sweeteners can cause previously healthy gut bacteria to become diseased and invade the gut wall, potentially leading to
New insight on how bacteria in the lungs protect against invading pathogens has been published today in the open-access eLife journal. The study in mice
Staphylococcus aureus is responsible for various diseases in humans, and recurrent infections are commonly observed. S. aureus produces an array of bicomponent pore-forming toxins that target and kill
Researchers have engineered Escherichia coli bacteria to make energy exclusively from carbon dioxide, according to a paper published today (November 27) in Cell. E. coli
Mosquitoes infected with Wolbachia bacteria and released into the wild are associated with a sharp decrease in dengue fever infections in humans, scientists reported Thursday
In the summer of 1924, Calvin Jr., President Coolidge’s youngest son, developed a blister in his third right toe while playing tennis at the White
Scientists have identified a molecule that stops gut microbes from breaking down the primary drug used to treat Parkinson’s disease — a step towards increasing
The US Food and Drug Administration issued a safety alert for fecal transplant procedures after two immune-compromised patients contracted drug-resistant infections, according to a statement
phytoplankton, which are responsible for half of the world’s primary production and are the basis of all marine ecosystems, have been declining for more than
People with phenylketonuria have to stick to strict diets to prevent the toxic buildup of phenylalanine, a key constituent of proteins, which otherwise can lead
Sticky bacteria tolerated as future food Dictyostelium discoideum amoebae consume bacteria until the supply is exhausted. Then the amoeba cells clump together into a “slug”
Sticky bacteria tolerated as future food Dictyostelium discoideum amoebae consume bacteria until the supply is exhausted. Then the amoeba cells clump together into a “slug”
Sticky bacteria tolerated as future food Dictyostelium discoideum amoebae consume bacteria until the supply is exhausted. Then the amoeba cells clump together into a “slug”
Bacteria can fend off viral infections by chopping up their DNA with their CRISPR-based immune system, but sufficient numbers of phages can overwhelm microbes’ defenses.
Efforts to combat the spread of infections, especially in health care settings, mostly involve the use of antibacterial cleaning agents and antibiotic drugs. Another possible
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