Abstract Pancreatic islets control glucose homeostasis by the balanced secretion of insulin and other hormones, and their abnormal function causes diabetes or hypoglycaemia. Here we
A new study by researchers from Case Western Reserve University may help explain the sex-based difference in the incidence rate of Alzheimer’s disease (AD) that makes women
Purpose To develop a safe and noninvasive in vivo assay of hepatic propionate oxidative capacity. Methods A modified 1-13C-propionate breath test was administered to 57
A new study published in Nature Communications shows that the age of bats can be predicted with high accuracy based on DNA methylation patterns. A
Researchers from the UCLA Jonsson Comprehensive Cancer Center say have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into
Unexpected transfer Gene therapy using adeno-associated viral (AAV) vectors is a promising strategy for monogenic blinding diseases. Leber hereditary optic neuropathy (LHON) is caused by
The CIITAdel keeps viruses at bay A better understanding of cellular mechanisms involved in viral resistance is needed for the next generation of antiviral therapies.
Although neurobiologist Oded Rechavi comes from a family of doctors and researchers, it was not his original plan to go into science. “It wasn’t something
According to a February 11 report from the Chinese Center for Disease Control and Prevention, the coronavirus known as 2019-nCoV has infected more than 42,000
The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Project published 23 papers today (February 5), including several in Nature, with insights from the genomes of more
Immune cells altered by CRISPR are safe to use in cancer patients, according to results of a clinical trial reported today (February 6) in Science.
As of today (January 23), 18 people have died from a newly identified coronavirus, and more than 630 have been infected. Airports are screening passengers
Discovery of a new T cell With all the extensive investigations scientists have conducted of the human immune system over the past century, it is
Trophoblasts, cells present during development in the fetus and placenta that also circulate in a pregnant woman’s bloodstream, could potentially be used for noninvasive prenatal
Earlier this year, the US Food and Drug Administration approved the most expensive drug ever to hit the market, a gene therapy for spinal muscular
From Alaska down to the Baja Peninsula, the rocky tide pools of North America’s West Coast are separated by hundreds of kilometers of sandy beaches.
A clinical trial of a gene therapy for Duchenne muscular dystrophy has been halted after a patient suffered serious side effects following treatment, Reuters reports
Researchers have identified a genetic mutation that may help mitigate the risk of some forms of Alzheimer’s. In a study published yesterday (November 4) in
A new gene editing technique called prime editing, tested in human and mouse cells, rewrites DNA by only cutting a single strand to add, remove,
Koalas are susceptible to cancers such as lymphoma and leukemia along with chlamydia infections due to koala retrovirus, a pathogen that began inserting itself into
A study of nematode worms, mice, and humans indicates that, across the animal kingdom, with aging comes more neural activity and when this natural increase
To date, most cases of uniparental disomy—having two copies of a chromosome from either mom or dad, rather than one from each—have been identified in
A study published in Nature Medicine that found an increased mortality rate in people with an HIV-preventing gene variant has a major flaw, according to
Molecules that combine elements of RNA and DNA, so-called chimeric molecules, may have been an important step in the emergence of life on Earth from
When I visited Ricaurte, Colombia, in 2016, I was surrounded by men with long faces and prominent ears. As we spoke, they would ask repetitive
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