Abstract Sexually dimorphic tissues are formed by cells that are regulated by sex hormones. While a number of systemic hormones and transcription factors are known
Abstract Glucocorticoid hormones (GCs) — acting through hippocampal mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) — are critical to physiological regulation and behavioural adaptation. We
Abstract Osteocalcin (OCN), the most abundant noncollagenous protein in the bone matrix, is reported to be a bone-derived endocrine hormone with wide-ranging effects on many
Characterized by a rise in heart rate, respiration, temperature, and adrenaline, the acute stress response, more commonly known as the fight-or-flight response, is a physiological
A genetic variant present in 5 percent of the population is tied to substantially lower blood levels of the active ingredient in a hormonal contraceptive
Abstract Harnessing female sex hormones may improve how all patients with melanoma respond to treatment. Main text Melanoma is a deadly form of skin cancer
Two people with a rare genetic disorder have helped shed light on the fundamental neuroscience of appetite and, scientists say, opened up a new target
G-protein-coupled receptors mediate the biological effects of many hormones and neurotransmitters and are important pharmacological targets1. They transmit their signals to the cell interior by
Summary Androgen receptor (AR) signaling is a distinctive feature of prostate carcinoma (PC) and represents the major therapeutic target for treating metastatic prostate cancer (mPC).
When animals eat, gut bacteria numbers spike. It also appears that the organisms have a means of limiting growth: by sending signals to their host
Proceedings of the National Academy of Sciences, August 1, 2011 DOI: 10.1073/pnas.1104383108 María Gutièrrez-Mecinas, Alexandra F. Trollope, Andrew Collins, Hazel Morfett, Shirley A. Hesketh, Flavie
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