Abstract Sickle cell disease is a growing health burden afflicting millions around the world. Clinical observation and laboratory studies have shown that the severity of
Grajevis Bakatunkanda’s mother knew the signs: when her son lost interest in dinner, that meant the pain was on its way. It would strike, like
Sickle cell disease is caused by an alteration in a single DNA base, but its clinical manifestations are influenced by other genes and behavioral and
The substitution of valine for glutamic acid in the β-chain of hemoglobin S (HbS) is associated with the formation of hemoglobin polymers that promote vaso-occlusion,
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