
A genome-wide genetic screen uncovers determinants of human pigmentation
Editor’s summary Skin pigmentation provides crucial protection from the DNA damage caused by sun exposure, but the production of melanin in the skin and hair
Editor’s summary Skin pigmentation provides crucial protection from the DNA damage caused by sun exposure, but the production of melanin in the skin and hair
Acne in action Adipogenesis plays a key role during deep tissue infection with Staphylococcus aureus, but the contribution of this process in acne caused by Cutibacterium acnes is
Patches of healthy tissue can contain groups of cells with genetic mutations, researchers reported June 6 in Science. In the study, they analyzed 29 different
Over the past 50 years, the frequency of allergies and autoimmune diseases has risen rapidly, but it’s not clear why. In a study published today
Highlights •Skin organoids can be generated from mPSCs under defined conditions •Skin organoids are composed of self-assembled epidermal and dermal layers •Skin organoids produce hair
Thanks to an international team of scientists and doctors, a seven-year-old Syrian refugee who lost most of his outer skin to a life-threatening genetic disease
Live imaging shows that healthy skin cells surround and expel neighbours that have cancer-promoting mutations, revealing that tissues can recognize and eliminate mutant cells to
Highlights •Stem cell lineage infidelity occurs transiently in wounds and persists in cancer •Wounds and cancer converge on lineage infidelity irrespective of stem cell origin
The device: Psoriasis is a chronic skin condition that causes itchy, scaly lesions over parts of the body. Engineered “designer cells,” placed in microcapsules and
Nature 480, 209-214 (2011); doi:10.1038/nature10649. P. Janich, G. Pascual, A Merlos-Suárez,E. Batlle, J. Ripperger et al. “The circadian molecular clock creates epidermal stem cell heterogeneity”.
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