The retirement debate: Stay at the bench, or make way for the next generation
Hans-Hilger Ropers vividly recalls the moment when he realized that he was running out of time to fulfil his scientific ambitions. It was at a
Hans-Hilger Ropers vividly recalls the moment when he realized that he was running out of time to fulfil his scientific ambitions. It was at a
Jews have a genetic predisposition to lymphoma, and due to Israel’s size, much of the population lives near agricultural areas and is exposed to pesticides
A key aspect of cancer metastases is the tendency for specific cancer cells to home to defined subsets of secondary organs. Despite these known tendencies,
As always, in addition to the scientific breakthroughs that make headlines throughout the year, there is also a dark side to science. From misconduct to
Neanderthals overlapped with early modern humans and, based on genetic evidence, eveninterbred. But the extent of the overlap of the two species both in terms
Scientists have uncovered two new cases of HIV patients in whom the virus has become undetectable. The two patients, both Australian men, became apparently HIV-free
Malaria changes the odor profiles of infected mice, making them at times more attractive to mosquitoes that transmit the malaria-causing parasite Plasmodium chabaudii, according to a
Patrick Harran, a chemist at the University of California, Los Angeles, will pay $10,000, develop and teach a lab-safety course, speak about the importance of
The prize in medicine will be awarded this year, to Israeli Prof. Nahum Sonenberg of McGill University in Montreal for his discovery of the proteins
The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2013 to Martin Karplus (Université de Strasbourg, France and Harvard
The 2013 Nobel Prize honours three scientists who have solved the mystery of how the cell organizes its transport system. Each cell is a factory
PLoS ONE 7, e44034 (2012) Chien-Yi Chang et al. “Unusual Long-Chain N-Acyl Homoserine Lactone Production by and Presence of Quorum Quenching Activity in Bacterial Isolates from Diseased
PNAS September 4, 2012 Gang Xiao et al. “Activator protein 1 suppresses antitumor T-cell function via the induction of programmed death 1” T cells play a
Nature 490,552–555 (25 October 2012) Sylvie Diochot et al. “Black mamba venom peptides target acid-sensing ion channels to abolish pain” The lethal bite of a
Nature Genetics 44,1178 (2012) Pamela Feliciano “Potential Parkinson disease and ALS drug” The aminopropyl carbazole compound P7C3 has previously been reported to have proneurogenic, neuroprotective
Nature Genetics 44, 1349–1354 (2012) David Whitcomb et al. “Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis” David Whitcomb, Bernie
Cell, Volume 151, Issue 5, 1083-1096, (Nov 2012) Wu et al. “Endocardial Cells Form the Coronary Arteries by Angiogenesis through Myocardial-Endocardial VEGF Signaling” Despite the profound impact
Cell, Volume 151, Issue 5, 937-950, (Nov 2012) Huang et al. “MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling” An
Science, 2012; Vol. 335 (6069), pp. 723-727; DOI: 10.1126/science.1214277 Schietinger, J. J. Delrow, R. S. Basom, J. N. Blattman and P. D. Greenberg. “Rescued Tolerant
Proceedings of the National Academy of Sciences, February 28, 2012, vol. 109 no. 9 3558-3563; Doi: 10.1073/pnas.1114748109 M.F. Sarhan, C.-C. Tung, F.V. Petegem and C.A.
Nature Chemistry, 2011; 3 (11): 875; DOI: 10.1038/nchem.1151 Garen G. Holman, Maha Zewail-Foote, Amy Rhoden Smith, Kenneth A. Johnson, Brent L. Iverson. “A sequence-specific threading
Nature Structural & Molecular Biology 18, 1336–1344 (2011). Doi: 10.1038/nsmb.2142. Lee, H.-R., Choi, W.-C., Lee, S., Hwang, J., Hwang, E., Guchhait, K., Haas, J., Toth,
Developmental Cell, Volume 22, Issue 1, 52-63, January 17, 2012. DOI: 10.1016/j.devcel.2011.10.014 . Mariana C.C. Silva, Dani L. Bodor, Madison E. Stellfox, Nuno M.C. Martins,
Nature (2012) doi:10.1038/nature10950 Yariv Kanfi, Shoshana Naiman, Gail Amir, Victoria Peshti, Guy Zinman, Liat Nahum, Ziv Bar-Joseph & Haim Y.Cohen A member of the celebrated
Science, Doi: 10.1126/science.1217421 Jeffrey N. Savas, Brandon H. Toyama, Tao Xu, John R. Yates and Martin W. Hetzer “Extremely Long-Lived Nuclear Pore Proteins in the
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