Molecular Medicine Israel

Single-Cell Analysis of Ovarian Cortex Fails to Find Stem Cells

The controversial oogonial stem cells eluded a team of Swedish researchers who mapped high-quality tissue samples of the human ovary, prompting more questions about the cells’ existence.

The first single-cell analysis of the human ovarian cortex revealed six main types of cells, but none of the oogonial stem cells that other researchers say they have isolated, according to a study published earlier this week (March 2) in Nature Communications. These findings are backed by the most advanced technologies, the authors say, and could put to rest a heated debate about the properties of the adult ovary that has raged for more than a decade….

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