Ebola virus (EBOV) glycoprotein (GP) can be recognized by neutralizing antibodies (NAbs) and is the main target for vaccine design. Here, we first investigate the
The CIITAdel keeps viruses at bay A better understanding of cellular mechanisms involved in viral resistance is needed for the next generation of antiviral therapies.
Discovery of a new T cell With all the extensive investigations scientists have conducted of the human immune system over the past century, it is
The world finally has an Ebola vaccine. On 11 November, European regulators approved a vaccine that has already helped to control deadly outbreaks of the
Researchers in Uganda are set to introduce a second experimental Ebola vaccine to the neighboring Democratic Republic of Congo, where the virus has claimed more
On Wednesday (July 17), the World Health Organization declared the Ebola outbreak in Democratic Republic of Congo a global health emergency. As of Tuesday (July
Half of isolated Ebola cases have gone undetected since the disease was first discovered in 1976, according to an analysis of outbreaks by scientists published
Health authorities in Uganda have approved the use of three experimental treatments against Ebola in the country. The decision comes in anticipation of spillover from
A child in Uganda has been diagnosed with Ebola — marking the first confirmed case in the country since an outbreak of the virus emerged
Violence in Democratic Republic of Congo is making it difficult for medical personnel to treat Ebola patients, according to The Washington Post. As of May
Researchers have discovered of a new genus of filovirus carried by fruit bats in China. The genome of the so-called Menglà virus shares sequences with
Although the Ebola outbreak in West Africa that started in 2013 was declared over more than a year ago, the disease lingers on. Many Ebola
The Ebola virus glycoprotein spike (white) bound by antibody fragments of the broadly neutralizing antibodies ADI-15878 (purple), ADI-15946 (blue), and ADI-16061 (green). Footprints of these
In 1927, Austrian physician Julius Wagner-Jauregg won the Nobel Prize in Physiology or Medicine for his discovery of the therapeutic value of malaria inoculation in
From blood samples of survivors of a 2007 Ebola outbreak in Uganda, researchers have isolated antibodies that are protective and can neutralize two other species
A few drops of blood are all that’s needed to test for Ebola using a newly approved paper-based diagnostic test. Approved by the World Health
The vicious cycle of Ebola infection does not end with the death of a victim. According to researchers with the National Institutes of Health (NIH),
Researchers investigating host responses to Ebola have long faced a significant disadvantage: the virus kills conventional lab mice, but does not produce the hemorrhagic fever
Two Liberian doctors are set to become the first Africans to receive an experimental drug against the Ebola virus. Once they are treated, existing supplies
Deadly Ebola probably touched down in Lagos, Nigeria, the largest city in Africa, on 20 July. A man who was thought to be infected with
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