![](https://www.molecular-medicine-israel.co.il/wp-content/uploads/2014/11/eye_scaled-300x168.jpg)
In vitro modeling and rescue of ciliopathy associated with IQCB1/NPHP5 mutations using patient-derived cells
Highlights •NPHP5-LCA patient-derived fibroblasts and RPE display abnormally elongated cilia •Outer segment protein localization is impaired in patient-derived photoreceptors •CEP290 protein reduction is observed across