Highlights Reduced aPKC drives HA deposition, the mCRC phenotype, and predicts poor survival• HA enhances malignancy and promotes CAF and epithelial heterogeneity in mCRC• Immunosuppression
Highlights Increasing evidence suggest that STAT2 and STAT3 control the expression of endothelial adhesion molecules [intercellular adhesion molecule (ICAM-1) and vascular cell adhesion molecule (VCAM-1)],
Scientists at UW Medicine’s Institute for Protein Design (IPD) in Seattle have created a new protein that mimics the action of a key immune regulatory
Glioblastoma, a highly malignant and usually fatal form of brain cancer, is resistant to treatment in part because it can quickly develop resistance to both
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