The level of magnesium in the blood is an important factor in the immune system’s ability to tackle pathogens and cancer cells. Writing in the
Abstract Despite the enormous therapeutic potential of immune checkpoint blockade (ICB), it benefits only a small subset of patients. Some chemotherapeutics can switch ‘immune-cold’ tumours
Highlights •High TMB correlates with efficacy of PD-1 plus CTLA-4 blockade in NSCLC •TMB and PD-L1 are independent variables •In multivariate analysis, TMB associated most
It sounds paradoxical, but chimeric antigen receptor (CAR) T cells can be more easy-going and more effective at killing cancer cells. Engineering a lackadaisical but
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