For years, scientists thought the brain lacked a lymphatic system, raising questions about how fluid, macromolecules, and immune cells escape the organ. In 2015, two
Researchers have developed lab-generated lymph node–like organoids that, when transplanted into mice in place of lymph nodes that have been removed, drain fluid and connect
Metastasizing cancer cells travel through the lymphatic vasculature, but it’s not clear what role the formation of lymph vessels, called lymphangiogenesis, plays in cancer progression.