RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance
Highlights • RAC1P29S activates PAK, AKT, and the SRF/MRTF transcription program in melanocytes • RAC1P29S induces a melanocytic to mesenchymal transition through SRF/MRTF and PAK