Abstract Lysine demethylase 5A (KDM5A) is a negative regulator of histone H3 lysine 4 trimethylation (H3K4me3), a histone mark associated with activate gene transcription. We
Multiple myeloma (MM) is a biologically heterogeneous malignancy, however, the mechanisms underlying this complexity are incompletely understood. We report an analysis of the whole-genome sequencing
The candidate drug daratumumab, which is a monoclonal antibody that targets the cell surface molecule CD38 (cluster of differentiation 38), was shown to be a
Results of a small clinical trial support the feasibility of using a multiple myeloma patient’s marrow-infiltrating lymphocytes (MILs) as the basis for adoptive T cell
Results of a small clinical trial support the feasibility of using a multiple myeloma patient’s marrow-infiltrating lymphocytes (MILs) as the basis for adoptive T cell
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