Significance Our results demonstrate that connexin 43 hemichannels are the conduits for amyotrophic lateral sclerosis (ALS) astrocyte-mediated motor neuron toxicity and disease spread, acting as
Removing disease-causing expansion Expansion in G4C2 RNA repeat in chromosome 9 open reading frame 72 (C9orf72) is one of the most common genetic causes of amyotrophic lateral
Network architecture is a brain-organizational motif present across spatial scales from cell assemblies to distributed systems. Structural pathology in some neurodegenerative disorders selectively afflicts a
Prior research has found that drinking a glass of red wine a day may protect against cardiovascular diseases, diabetes, and neurodegenerative disorders. The latest laboratory
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