For years, neurons in the brain were assumed to all carry the same genome, with differences in cell type stemming from epigenetic, transcriptional, and posttranscriptional
Delivering a CRISPR/Cas9–based therapy directly to the eye via a viral vector can prevent retinal degeneration in a mouse model of retinitis pigmentosa, a team
The human cerebral cortex experiences a burst of growth late in fetal development thanks to the expansion and migration of progenitor cells that ultimately form
Mutations in a zinc-finger transcription factor known as Zic2 cause problems in cortical development and can result in schizophrenia symptoms. Studying embryonic mice, Murillo et
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