Found: A Cancer Drug’s Mechanism of Action
Scientists have known that the cancer drug ONC201 blocks cells from proliferating and kills tumors in cell and animal models—but they haven’t known exactly how
Scientists have known that the cancer drug ONC201 blocks cells from proliferating and kills tumors in cell and animal models—but they haven’t known exactly how
Checkpoint inhibitor drugs, those that pull the brakes off the immune system, can cause dramatic improvements in cancer patients, but the benefits are far from
Metastasizing cancer cells travel through the lymphatic vasculature, but it’s not clear what role the formation of lymph vessels, called lymphangiogenesis, plays in cancer progression.
Platelets do more than promote clotting. They weaken one of the body’s immune defenses against cancer. Unfortunately, platelets tend to work against the immuno-oncology treatments
For more than half a century, the treatment of cancer has relied heavily on radiation, surgery, chemotherapy and, increasingly, the use of drugs that target
Alfred Knudson, best known for revealing through mathematics how cancers emerge, died July 10, according to a statement by the Fox Chase Cancer Center in
Dozens of genetic mutations are known to facilitate cancer progression, but metastasis doesn’t appear to be controlled by additional changes to the genome. A study
Antioxidants decrease the levels of DNA-damaging, cancer-causing reactive oxygen species (ROS) that are formed during normal metabolism. Yet clinical trials that evaluated the health benefits
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