
Mutation in SARS-CoV-2 Variant Does Not Affect Vaccine: Study
Serum samples from 20 individuals who received the Pfizer-BioNTech vaccine against SARS-CoV-2 thwarted a version of the coronavirus with the so-called N501Y mutation, according to
Serum samples from 20 individuals who received the Pfizer-BioNTech vaccine against SARS-CoV-2 thwarted a version of the coronavirus with the so-called N501Y mutation, according to
Spinal cord injury (SCI) often causes severe and permanent disabilities due to the regenerative failure of severed axons. Here we report significant locomotor recovery of
Enhancing EGFR to offset osteoarthritis Cartilage degeneration in osteoarthritis causes pain and limits mobility. Wei et al. investigated epidermal growth factor receptor (EGFR) signaling as a potential
It was a Friday afternoon in March 2013 when Andy Geall got the call. Three people in China had just become infected with a new
Researchers from the UCLA Jonsson Comprehensive Cancer Center say have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into
People with the advanced form of multiple sclerosis (MS) called secondary progressive MS who took the drug siponimod for one to two years had improved
Unexpected transfer Gene therapy using adeno-associated viral (AAV) vectors is a promising strategy for monogenic blinding diseases. Leber hereditary optic neuropathy (LHON) is caused by
Loss of visual acuity is a common feature of aging, whether it’s from age-related conditions such as glaucoma, an impaired ability for cells to respond
New insight on how bacteria in the lungs protect against invading pathogens has been published today in the open-access eLife journal. The study in mice
Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study by
Earlier this month, the world finally received some good news about COVID-19. Interim results from Phase 3 clinical trials revealed that two vaccine candidates —one from
Highlights •2- and 3-antigen AND or NOT logic gates improve tumor discrimination of CAR T cells •All transmembrane antigen combination pairs and triples are computationally screened
ABSTRACT SARS-CoV-2 is causing a second outbreak so the hope for its complete eradication is far from happening. In the absence of effective vaccines, it
Current chemotherapy regimens slow cancer progression and save lives, but these powerful drugs affect both healthy and cancerous cells. Now, researchers reporting in ACS’ Nano
Abstract Harnessing CRISPR-Cas9 technology for cancer therapeutics has been hampered by low editing efficiency in tumors and potential toxicity of existing delivery systems. Here, we
Researchers have discovered a previously unknown way that pancreatic cells decide how much insulin to secrete. It could provide a promising new target to develop
Pfizer and partner BioNTech said Monday that their vaccine against Covid-19 was strongly effective, exceeding expectations with results that are likely to be met with cautious excitement
A basic treatment for leukemia For patients with acute myeloid leukemia, hematopoietic stem cell transplant offers a chance of curing the underlying cancer, in part
EVidence of tolerance Multiple sclerosis (MS) is an autoimmune disorder characterized by neuroinflammation and demyelination. Administration of myelin-specific self-antigens to induce tolerance has been shown
Physicians and researchers have had questionable success treating patients with severe COVID-19 with either antibody-based drugs or convalescent plasma. Neither of those strategies is a cell-based therapy, and,
Highlights •Predicting triplet stimuli effects in vitro using coculture data from singles and pairs •Singles and pairs dictate the information signaled by triplets in mouse and human DCs
The catastrophic global health and socioeconomic impact of COVID-19, together with the absence of any clearly effective preventive or therapeutic remedies, has created a massive
When US President Donald Trump was ill with COVID-19, his physicians administered a bevy of medications — some proven, others experimental. But there is one
The U.S. Food and Drug Administration has approved the antiviral drug Veklury (remdesivir) for use in adult and pediatric patients 12 years of age and older and
Unlike fine wine, the human body does not improve with age. Hearing fades, skin sags, joints give out. Even the body’s immune system loses some
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