SARS-CoV-2, the virus responsible for COVID-19, has wreaked havoc on health care systems, economies and everyday lives worldwide. Scientists are fighting back with multiple strategies,
Whether it takes weeks, as US President Donald Trump has hinted, or months, as most health-care experts expect, an approved vaccine against the coronavirus is
The results are in from the first monoclonal antibody drug for COVID-19 tested in humans. The small Phase 2 clinical trial involving 452 participants shows
Ever since the first cases of a mysterious disease in the early 1980s exploded into the HIV/AIDS pandemic, researchers have been searching for ways to
A drug used to treat gout, probenecid, may improve heart function in individuals with a particular heart defect, according to results from a small pilot
rthritis affects almost 2% of the world’s population, or some 150 million people, and currently, there is no completely effective treatment for this chronic disease.
In an animal model of multiple sclerosis (MS), decreasing the amount of a protein made in the liver significantly protected against development of the disease’s
An experimental vaccine is effective at preventing pneumonia in mice infected with the COVID-19 virus, according to a study from Washington University School of Medicine
In a study led by EPFL, scientists have developed a synthetic blood-thinner that, unlike all others, doesn’t cause bleeding side-effects. The highly potent, highly selective,
Valneva SE (“Valneva”), a specialty vaccine company focused on prevention of diseases with major unmet needs, today announced positive initial results for its first Phase
Head and neck squamous cell carcinoma (HNSCC) develops in the mucous membranes of the mouth, nose, and throat. It is an aggressive life-threatening disease associated
Highlights Increasing evidence suggest that STAT2 and STAT3 control the expression of endothelial adhesion molecules [intercellular adhesion molecule (ICAM-1) and vascular cell adhesion molecule (VCAM-1)],
In a press release on Tuesday (June 16), researchers from a large, randomized controlled trial for COVID-19 treatments announced that they’d seen an improvement in survival at
A Chinese company will turn to Brazil for help. The World Health Organization (WHO) is adopting a strategy forged in a war zone during an
Highlights COPD is the third leading cause of death globally, and there is an urgent unmet medical need to develop novel therapeutics specifically for COPD.
Thanks to a remarkable feat of natural molecular engineering that allows our bodies to generate countless different kinds of antibodies against pathogens, COVID-19 survivors typically
For some COVID-19 patients, the body’s immune response may be as destructive as the virus that causes the disease. The persistent high fevers, severe respiratory
One of the oldest vaccines could protect us against our newest infectious disease, COVID-19. The vaccine has been given to babies to protect them against
Two pediatric brain cancers that are challenging to treat if they recur, medulloblastoma and ependymoma, are the target of a clinical trial using a new
Repaired β cells for replacement therapy Wolfram syndrome is a recessive genetic disease caused by mutations in WFS1 (Wolfram syndrome 1) and can present with a multitude
Abstract Medical devices and implants made of synthetic materials can induce an immune-mediated process when implanted in the body called the foreign body response, which
Abstract Techniques for exclusion of exons from mature transcripts have been applied as gene therapies for treating many different diseases. Since exon skipping has been
Abstract A coronavirus (HCoV-19) has caused the novel coronavirus disease (COVID-19) outbreak in Wuhan, China. Preventing and reversing the cytokine storm may be the key
Abstract Background Chloroquine and hydroxychloroquine have been found to be efficient on SARS-CoV-2, and reported to be efficient in Chinese COV-19 patients. We evaluate the
Abstract At the time of writing this commentary (February 2020), the coronavirus COVID‐19 epidemic has already resulted in more fatalities compared with the SARS and
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