Highlights Summary The currently accepted intestinal epithelial cell organization model proposes that Lgr5+ crypt-base columnar (CBC) cells represent the sole intestinal stem cell (ISC) compartment. However,
Editor’s summary Regulating cytokine activity can effectively manage inflammatory bowel disease, but traditional treatments are immunosuppressant or only target specific cytokines. By combining the robust
Highlights •Nav1.8+CGRP+ nociceptors neighbor goblet cells and induce rapid mucus secretion •Commensals trigger CGRP release, which signals to Ramp1 expressed by goblet cells •Nociceptor or Ramp1
Abstract Guided by gut sensory cues, humans and animals prefer nutritive sugars over non-caloric sweeteners, but how the gut steers such preferences remains unknown. In
New research has discovered that common artificial sweeteners can cause previously healthy gut bacteria to become diseased and invade the gut wall, potentially leading to
Understanding the appropriate balance of “good” bacteria within the intestinal tract has been the focus of much ongoing research for a number of years. Links
The evidence continues to mount over the importance of the human microbiome—especially within the intestinal tract—for supporting optimal growth and overall health and wellness. Over
Gut microbes have ascended to prominence as key modulators of host immunity, raising the possibility that they could influence the outcome of cancer immunotherapy. Two
Created by ePubSystems. Contact Us for similar site for your university or institute.