Abstract Doxorubicin, the most prescribed chemotherapeutic drug, causes dose-dependent cardiotoxicity and heart failure. However, our understanding of the immune response elicited by doxorubicin is limited.
Abstract The development of new immunotherapies to treat the inflammatory mechanisms that sustain atherosclerotic cardiovascular disease (ASCVD) is urgently needed. Herein, we present a path
Highlights • Structure of PCSK9/CHRD and an inhibitory nanobody that prevents LDLR degradation.• Binding of CAP1 to PCSK9 enhances its activity and abrogates nanobody inhibition.•
A drug used to treat gout, probenecid, may improve heart function in individuals with a particular heart defect, according to results from a small pilot
Microorganisms on the tongue could help diagnose heart failure, according to research presented on HFA Discoveries, a scientific platform of the European Society of Cardiology
Injecting human cardiac muscle cells into monkeys that suffered heart attacks helped the animals’ damaged hearts pump blood better, researchers report July 2 in Nature
Left main coronary artery disease is associated with high morbidity and mortality owing to the large amount of myocardium at risk. European and U.S. guidelines
If you’re looking to improve your heart health by changing your diet, when you eat may be just as important as what you eat. In
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