Highlights Summary Recent findings show that effective integration of novel information in the brain requires coordinated processes of homo- and heterosynaptic plasticity. In this work,
Highlights •We made a light-weight 2-photon miniscope for calcium imaging in freely moving mice •Stable high-quality imaging was observed during a wide spectrum of behaviors
Summary The occurrence of dreaming during rapid eye movement (REM) sleep prompts interest in the role of REM sleep in hippocampal-dependent episodic memory. Within the
Neuroscientist Gregor Pilz of the University of Zurich has watched stem cells turn into neurons in the brains of young, living mice—a feat that not
For a small fold of tissue, the hippocampus has an outsized influence. It stores and retrieves human memories, capturing the life history that makes us
It’s well established that exercise is good for the mammalian brain. As early as 1999, researchers discovered considerably more newborn neurons in the hippocampi of
Researchers in the UK and New Zealand have created the largest-ever database of protein expression changes associated with Alzheimer’s disease, according to a study published
Highlights • Single-cell mass spectrometry reveals a novel glutamate biosynthetic pathway in brain • UV exposure leads to elevated blood and brain levels of urocanic
New neurons may not develop in the adult human brain as neuroscientists for years have come to believe. Researchers studying postmortem brain tissue of humans
Newly made cells in the brains of mice adopt a more complex morphology and connectivity when the animals encounter an unusual environment than if their
Scientists at the Gladstone Institutes have discovered how the major genetic risk factor for Alzheimer’s disease causes memory impairment. A specific type of brain activity
Scientists at the Gladstone Institutes have discovered how the major genetic risk factor for Alzheimer’s disease causes memory impairment. A specific type of brain activity
For decades, researchers have known that forming memories requires that the expression and translation of some genes be upregulated in the brain. Unexpectedly, the mouse
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