
Malaria cases are falling worldwide
The number of malaria infections recorded globally has fallen for the first time in several years, according to the World Health Organization (WHO), which published
The number of malaria infections recorded globally has fallen for the first time in several years, according to the World Health Organization (WHO), which published
A measles outbreak in Samoa has killed 53 people since late October, including 50 children, the Samoan government reported today (December 2). Samoan Prime Minister
About half a million people, most of them children living in Africa, are killed each year by malaria1. Management of malaria, particularly that caused by
Nigeria, Democratic Republic of Congo, Central African Republic, and Angola have experienced nine new cases of polio caused by the live virus in oral polio
An antiflu medication first approved in Japan in 2018 and given the green light later that year in the US may be fostering the emergence
The world finally has an Ebola vaccine. On 11 November, European regulators approved a vaccine that has already helped to control deadly outbreaks of the
Autoimmune diseases tend to ease up during pregnancy, and for women with multiple sclerosis, physicians have documented fewer relapses of the condition while women are
In a large trial, a dengue immunization developed by Takeda Vaccines reduced the number of dengue by more than 80 percent relative to a control
An experimental vaccine continues to show promise in preventing active tuberculosis infections in patients with the latent form of the disease, researchers reported yesterday (October
Children who survive measles are protected against future measles infections, but have such diminished immunity that they may be left vulnerable to other pathogens, according
There’s a lot that scientists don’t know about the gut microbiota, and when it comes to the viruses present there they know even less. To
In the early 2000s, Arturo Zychlinsky at the Max Planck Institute for Infection Biology in Berlin found that mammalian immune cells called neutrophils use an
Chikungunya virus (CHIKV) is a re-emerging alphavirus that is transmitted to humans by mosquito bites and causes musculoskeletal and joint pain1,2. Despite intensive investigations, the
B cells are important in the pathogenesis of many, and perhaps all, immune-mediated diseases. Each B cell expresses a single B cell receptor (BCR)1, and
A few years ago, while using DNA sequencing to study the lung microbiomes of people who had received lung transplants, researchers at the University of
When Jonathan Epstein first looked through the microscope to examine the results of a study using CAR T cells in mice, he didn’t know whether
Mounting evidence in animal models, as well as correlative studies in humans, indicate that the microbes present in the gut can shape immune responses. In
The immune system has evolved complex mechanisms that allow rapid and destructive responses to microbial intruders while sparing the host’s own tissues. Regulation of this
Immune cells called macrophages commonly function as scavenger-like (phagocytic) cells that ingest and remove damaged cells. Writing in Nature, Culemann et al.1 report that the
An effective immune response to general signs of infection, regulated by the branch of the immune system called innate immunity, is essential for the removal
Scientists extracted a near-complete HIV-1 genome from a lymph node that had been preserved in wax for more than 50 years. The sample stands as
A new cryopreservation bank offers customers the chance to stash away their T cells for use in future cancer treatments. Using a similar model to
Drugs work stunningly well to control HIV—but not in everyone, and not without side effects. That’s why a small cadre of patients known as elite
Researchers in Uganda are set to introduce a second experimental Ebola vaccine to the neighboring Democratic Republic of Congo, where the virus has claimed more
To create an individualized cancer vaccine, researchers must identify cancer-specific peptides called neoantigens, then use a cell-, protein-, or nucleic acid–based platform to deliver those
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