FDA Approves First-In-Class CAR T Cell Immunotherapy for Leukemia
Today, August 30, 2017, the U.S. Food and Drug Administration approved a revolutionary, first-in-class cancer immunotherapy for children and young adults with relapsed or refractory
Today, August 30, 2017, the U.S. Food and Drug Administration approved a revolutionary, first-in-class cancer immunotherapy for children and young adults with relapsed or refractory
By her 50th birthday, Els van der Heijden felt sicker than ever. Born with the hereditary disorder cystic fibrosis (CF), she had managed to work
Abstract Streptococcus mutans employs a key virulence factor, three glucosyltransferase (GtfBCD) enzymes to establish cariogenic biofilms. Therefore, the inhibition of GtfBCD would provide anti-virulence therapeutics.
An accidental spill in the lab has led to the development of bioactive “tissue papers” that could act as a scaffold to grow cells and
Engineering human livers is a lofty goal. Human liver cells, hepatocytes, are particularly difficult to grow in the laboratory as they lose liver functions quickly
t takes a trained eye to determine whether you’ve succeeded in turning a skin cell into a stem cell, or to distinguish between two related
Researchers in Portugal studying a rare type of hybrid fish in the Ocreza River have found an individual that is the exact genomic match to
Peripheral clearance of amyloid-β (Aβ) by peritoneal dialysis could help to reduce the amyloid plaque burden in the brain, and might, therefore, represent a new
Two teams of scientists have generated blood stem cells by reprogramming either human or mouse cells. In both cases, these hematopoietic stem cells successfully produced
Abstract Macrophages have diverse functions in immunity as well as development and homeostasis. Here we identify a function for these cells in long distance communication
Emerging additive manufacturing techniques enable investigation of the effects of pore geometry on cell behavior and function. Here, we 3D print microporous hydrogel scaffolds to
Background Long-term intraocular injections of vascular endothelial growth factor (VEGF)-neutralising proteins can preserve central vision in many patients with neovascular age-related macular degeneration. We tested
Type I diabetes had rendered a 43-year-old woman dependent on insulin, until doctors restored her body’s ability to produce the hormone with engineered islet cells
Deep in the basement archives of London’s Great Ormond Street Hospital for Children reside the patient records that cancer researcher Sam Behjati hopes will put
During senescence, cells remain in a state of growth arrest. Accumulation of similar nonfunctional cells has been linked to chronic inflammatory diseases and degenerative disorders.
From the dry valleys of Antarctica to the depths of a Welsh coal mine, a promised revolution in genome sequencing may finally be catching fire.
When the immune system has eliminated the last traces of Zika virus from the blood, low-level infection may continue at certain sites around the body.
Highlights •Stem cell lineage infidelity occurs transiently in wounds and persists in cancer •Wounds and cancer converge on lineage infidelity irrespective of stem cell origin
Rapid and simple assays to detect infectious agents are key to tracking emerging epidemics. Chotiwan et al. describe a loop-mediated amplification (LAMP) assay that detects
A way to switch off IBD Inflammatory bowel diseases (IBDs) such as ulcerative colitis and Crohn’s disease are associated with defective interleukin-10 (IL-10) signaling. Although
Therapies using T cells that are programmed to express chimeric antigen receptors (CAR T cells) consistently produce positive results in patients with hematologic malignancies. However,
When people get sick, they often think of bacteria as the cause of their illness and wouldn’t even begin to think of bacteria as having
Conventional chemotherapy with DNA-damaging agents has helped countless cancer patients become cancer survivors. This successful outcome is sometimes accompanied by long-term side effects, however. In
Conventional chemotherapy with DNA-damaging agents has helped countless cancer patients become cancer survivors. This successful outcome is sometimes accompanied by long-term side effects, however. In
Sickle cell disease is caused by an alteration in a single DNA base, but its clinical manifestations are influenced by other genes and behavioral and
Created by ePubSystems. Contact Us for similar site for your university or institute.