Mice Gene-Edited While Still in the Womb
Sientists have used CRISPR technology to edit out a lung-disease–causing gene while mice were in utero, rescuing the function of the lung and not affecting
Sientists have used CRISPR technology to edit out a lung-disease–causing gene while mice were in utero, rescuing the function of the lung and not affecting
Blasco et al. show that ablation of Egfr and Raf1 results in complete regression of a subset of mutant Kras/Trp53-induced pancreatic ductal adenocarcinomas (PDAC) without
A person with HIV seems to be free of the virus after receiving a stem-cell transplant that replaced their white blood cells with HIV-resistant versions.
An international team of researchers, including scientists at the Royal College of Surgeons in Ireland (RCSI), has discovered 11 new genes associated with epilepsy. The
A team of cancer researchers has identified a pair of enzymes that they say could serve as therapeutic targets whose inhibition would block the growth
Highlights •NOTCH signaling is preferentially activated in glioblastoma stem cells •GSIs have limited activities against glioblastoma stem cells •FTIs improve response to GSIs in vitro
A patient’s own cells can be engineered to combat cancer. Called a “living drug”, the cells hunt and destroy cancer cells, sometimes adding years to
Today, August 30, 2017, the U.S. Food and Drug Administration approved a revolutionary, first-in-class cancer immunotherapy for children and young adults with relapsed or refractory
Texas last week signaled its defiance of the federal government over unproven stem cell therapies, which are widely offered in the state for conditions including
During senescence, cells remain in a state of growth arrest. Accumulation of similar nonfunctional cells has been linked to chronic inflammatory diseases and degenerative disorders.
Chronic myeloid leukaemia (CML) is driven by the activity of the BCR–ABL1 fusion oncoprotein. ABL1 kinase inhibitors have improved the clinical outcomes for patients with
The creative minds at MIT have just devised a new strategy to target and abolish cancerous tumors. In the new study—published recently in Nature Communications
In 2015, 17 million HIV-infected individuals worldwide were on antiretroviral drug therapies, which are remarkably effective in suppressing the virus. Yet, 6000 people a day
Summary Vaccines for human papillomavirus (HPV), given to girls to prevent cervical cancer, have come under fire in several countries for allegedly causing such side
Roche said today it will launch a CHF 100 million ($100.1 million) global network of 21 academic centers focused on cancer immunotherapy R&D. The new
Roche said today it will launch a CHF 100 million ($100.1 million) global network of 21 academic centers focused on cancer immunotherapy R&D. The new
Transcription factors have long been viewed as “undruggable” targets for therapy: however, this concept may now need some tweaking. Cho et al. found that a
Over the years vitamin C supplementation has had a tumultuous relationship with empirical science. In 1753, James Lind, a Scottish surgeon with the British Royal
Vice President Joe Biden, in describing the cancer research initiative President Obama asked him to lead, said “the goal of this initiative—this ‘moonshot’ is to
The hottest technique in gene editing, called CRISPR, could soon be used to study human embryos. On 14 January, a regulatory committee in the United
Merck & Co. said this afternoon it has acquired IOmet Pharma, a small-molecule drug developer focused on cancer immunotherapy and cancer metabolism, for an undisclosed
Merck & Co. said this afternoon it has acquired IOmet Pharma, a small-molecule drug developer focused on cancer immunotherapy and cancer metabolism, for an undisclosed
A well-powered clinical trial that failed to replicate promising results in animal models of fragile X syndrome yields important lessons for clinical trial design (Berry-Kravis
It sounds paradoxical, but chimeric antigen receptor (CAR) T cells can be more easy-going and more effective at killing cancer cells. Engineering a lackadaisical but
Chinese stem-cell scientists have welcomed long-awaited measures that, state media claim, will rein in rogue use of stem cells in clinics while allowing research. The
Created by ePubSystems. Contact Us for similar site for your university or institute.