Tiny, Motorized Pill Delivers Vaccine to Mouse Intestine
A new type of vaccine vehicle—this one literally has a teeny tiny motor—can drive itself to the mucosal linings of mouse intestines, potentially allowing for
A new type of vaccine vehicle—this one literally has a teeny tiny motor—can drive itself to the mucosal linings of mouse intestines, potentially allowing for
Nanoparticles of indium phosphide—a semiconducting material used in solar cells—installed onto the surface of Saccharomyces cerevisiae allows the yeast to use light to fuel biosynthetic
Two studies in mice published today (October 31) in Nature report the existence of several types of brain cells that had not been acknowledged before.
For the first time, researchers have used the DNA from two mouse mothers to create healthy pups, some of which matured and had their own
Researchers at Caltech have designed a noninvasive method to control specific neural circuits in the mouse brain. The technique, published earlier this week (July 9)
CRISPR gene editing can create large numbers of unwanted DNA changes that may go undetected, researchers report today (July 16) in Nature Biotechnology. The findings
Researchers used magnetically driven microrobots to carry cells to predetermined spots within living zebrafish and mice, they report in Science Robotics today (June 27). The
Highlights Somatic mosaicism resulting from post-zygotic mutations has been shown to contribute to many diseases including brain-related disorders, in addition to cancer. Emerging data also
Adult human hippocampi are home to thousands of immature neurons, researchers report today (April 5) in Cell Stem Cell. The result runs counter to a
Camelids such as camels, llamas, and alpacas make an unusual class of antibodies with a growing number of applications in biomedical science. But researchers wanting
The Nobel Prize in Chemistry was awarded this morning (October 4) to three scientists who developed cryo-electron microscopy, a method that allows scientists to freeze
Today, August 30, 2017, the U.S. Food and Drug Administration approved a revolutionary, first-in-class cancer immunotherapy for children and young adults with relapsed or refractory
A popular chemogenetic technique for controlling cells does not operate in vivo in the way scientists had assumed. Reporting in Science yesterday (August 3), researchers
Neural stem cells normally go with the flow of chemical guides. But with a little electrical stimulation they can be coaxed to go the other
Two teams of scientists have generated blood stem cells by reprogramming either human or mouse cells. In both cases, these hematopoietic stem cells successfully produced
During senescence, cells remain in a state of growth arrest. Accumulation of similar nonfunctional cells has been linked to chronic inflammatory diseases and degenerative disorders.
Researchers at the Gladstone Institutes and several other institutions say they have discovered that changing a specific part of the huntingtin protein prevented the loss
The term “life hacking” usually refers to clever tweaks that make your life more productive. But on p. 819, a team of scientists comes a
The National Institutes of Health soon expects to lift a moratorium on funding for controversial experiments that add human stem cells to animal embryos, creating
A new study led by investigators at the University of Glasgow has identified how cells protect themselves against misfolded and aggregated proteins known to be
Injecting cancerous tumors with microscopic particles and then zapping them with lasers seems like an idea ripped straight from the pages of science fiction. Yet,
Artemisinin-based therapies are the only effective treatment for malaria, the most devastating disease in human history. To meet the growing demand for artemisinin and make
Abstract Malignant tumors shed DNA into the circulation. The transient half-life of circulating tumor DNA (ctDNA) may afford the opportunity to diagnose, monitor recurrence, and
A synthetic genetic circuit that mimics the quorum-sensing systems used by bacterial populations to coordinate gene expression enables bacteria to deliver drugs to mouse tumours
Researchers at the US National Cancer Institute (NCI) have successfully visualized the structures of enzymes at near-atomic resolutions previously not considered possible, using cryo-electron microscopy
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