Researchers have shown that reprogramming T cells to target glioblastoma in mice resulted in control of these tumors. The approach, shown to be safe in
A scientist at the University of Buffalo used an FDA-approved drug and human stem cells to increase the production of myelin in a myelin-deficient mouse
Although both papers describing stimulus-triggered acquisition of pluripotency (STAP) a simple procedure to reprogram stem cells have been retracted, there’s been some lingering hope that perhaps
The stem cell field was rocked earlier this year by investigations into researchers’ claims to have reprogrammed somatic cells into pluripotent progenitors without the aid
Eggs and sperm do it when they combine to make an embryo. John Gurdon did it in the 1960s, when he used intestinal cells from
Eggs and sperm do it when they combine to make an embryo. John Gurdon did it in the 1960s, when he used intestinal cells from
Eggs and sperm do it when they combine to make an embryo. John Gurdon did it in the 1960s, when he used intestinal cells from
Researchers from Mount Sinai Hospital’s Lunenfeld-Tanenbaum Research Institute and their international colleagues have uncovered a new type of pluripotent mouse stem cell the “F-class” cell
Until recently, cell sorting was a constant topic of conversation in Stacy Blain’s lab and not in a good way. Blain, an assistant professor of
The technique: Imagine pulling a small piece of paper out of your desk drawer, adding a drop of water, and within hours having a reconstituted
A Japanese woman in her 70s is the world’s first recipient of cells derived from induced pluripotent stem cells, a technology that has created great
In 2008, a team led by Stanford University’sChristina Smolke, then at Caltech, showed in Nature Chemical Biology that engineered yeast (Saccharomyces cerevisiae) could produce benzylisoquinoline alkaloid (BIA)
Cancer cells in the blood can now be isolated and studied in culture, opening up the possibility of personalizing treatment strategies. Tumours shed small amounts
There are two methods for reprogramming mature cells to pluripotent stem cells, which can give rise to all cells of the body. The first direct
Researchers have taken another step toward creating a functional human retina in the laboratory. Previous studies showed that an early-stage retina, including photoreceptors with primary
Currently, there are no clinically approved surgical glues that are nontoxic, bind strongly to tissue, and work well within wet and highly dynamic environments within the body.
The device: A miniscule diamond flaw—just two atoms different—could someday enable researchers to image single molecules without resorting to time-consuming and technically exacting X-ray crystallography. The
Cell, 14 July 2011 Frank Soldner et al. “Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations.” A method
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