Highlights •Measuring immunity to SARS-CoV-2 is key for understanding COVID19 and vaccine development •Epitope pools detect CD4+ and CD8+ T cells in 100 and 70% of convalescent
Our digestive systems harbour more bacterial cells than there are human cells in our bodies. Although the often-mentioned estimate of a tenfold excess of microorganisms
The development of broad-spectrum antiviral drugs particulary in the context of emerging zoonotic infections for which specific interventions do not exist sheahnan et al. tested
Summary Due to the rapid emergence of antibiotic-resistant bacteria, there is a growing need to discover new antibiotics. To address this challenge, we trained a
Abstract Background Chloroquine and hydroxychloroquine have been found to be efficient on SARS-CoV-2, and reported to be efficient in Chinese COV-19 patients. We evaluate the
A Phase 1 clinical trial evaluating an investigational vaccine designed to protect against coronavirus disease 2019 (COVID-19) has begun at Kaiser Permanente Washington Health Research
TRIKAFTA is the third drug approved by the FDA that rescues defects caused by the major mutation F508del. It is superior to its predecessors that
Tuberculosis is the deadliest human infection, killing 1.5 million people in 2018 alone (go.nature.com/2kbuiq). It is widely accepted that an effective vaccine against the bacterium
There is a mountain of evidence to support that a high body mass index (BMI) and obesity negatively impact cancers, diabetes, cardiovascular, and other diseases.
A treatment regimen for extensively drug-resistant tuberculosis could help stem the growing problem of hard-to-treat TB infections in developing countries, according to the Associated Press.
The US Food and Drug Administration issued a safety alert for fecal transplant procedures after two immune-compromised patients contracted drug-resistant infections, according to a statement
Escherichia coli is capable of synthesizing drug-resistant proteins even in the presence of antibiotics designed to cripple cell growth. That’s the finding by a group
Modifying levels of vasopressin, a hormone related to oxytocin that is involved in the regulation of mammalian social behavior, could enhance social function in people
Long-acting medicines have proved as effective as daily pills in preventing HIV from replicating, according to results from twin trials that enrolled more than 1,000
Plasmodium falciparum resistance to artemisinin-based combination therapies (ACTs) started to crop up around 2007. Infections, especially in the Greater Mekong area of Southeast Asia, seemingly
For the second time, a person living with HIV appears to have cleared the virus after a stem cell transplant replaced his infected immune cells
The US Food and Drug Administration has approved esketamine to treat adults whose depression hasn’t responded to other antidepressants, the agency announced in a statement
Messenger RNA has been viewed as a potential therapy for several diseases for many years. However, the biggest obstacle to this approach so far has
Scientists at the Weizmann Institute of Science have identified a molecular pathway in the brain that can be targeted to reduce anxiety. Their studies showed
The stunning failure of a once-promising cancer drug has got some researchers arguing that the field has moved too fast in its embrace of therapies
The stunning failure of a once-promising cancer drug has got some researchers arguing that the field has moved too fast in its embrace of therapies
In carcinomas, cancer cells often win the loyalty of neighboring cells, stromal cells, that should know better. Rather than stand aside and let the immune
Antibiotic-resistant infections could kill 2.4 million people in Europe, North America, and Australia by 2050 without further action to combat the infections, according to a
The development of resistance to cancer therapy is a major predictor of patient mortality. Therefore, understanding resistance mechanisms is key to improving therapeutic outcomes. Writing
Low-dose aspirin is a popular daily prevention strategy for individuals with a history of heart attack or stroke, owing to aspirin’s ability to reduce the
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