
Scientists use a “big data” approach to precision medicine
In a new study, researchers compared genetic mutations in patient tumours to those in cancer cell lines and then tested the cell lines’ responses to
In a new study, researchers compared genetic mutations in patient tumours to those in cancer cell lines and then tested the cell lines’ responses to
The malaria vaccine doesn’t provide lasting protection against the mosquito-borne disease, according to a study published yesterday (June 29) in NEJM: it delays infections by
Researchers have identified a gene that kickstarts the male-specific genetic program in the African malaria mosquito Anopheles gambiae. When expressed in genetically female mosquito embryos,
Patients who receive blood stem cells from a donor run a risk of developing immediate life-threatening infections and, a month or so later, graft-versus-host disease
An antibody to block viral fusion A small fraction of HIV-1–infected individuals develop broad and potent antibodies that bind the HIV-1 envelope protein (Env). These
Two companies in Brazil are taking a creative approach to controlling populations of Zika-carrying mosquitoes: creating billboards that mimic the smell of human breath and
As we age, our immune systems change; in many ways not for the better. For instance, the elderly account for 90% of influenza deaths annually.
The ongoing Zika virus epidemic is of grave concern because of its apparent links to congenital microcephaly and Guillain-Barré syndrome. Sirohi et al. present a
Obesity stimulates chronic inflammation in adipose tissue, which is associated with insulin resistance, although the underlying mechanism remains largely unknown. Here we showed that obesity-related
The lead in the water in Flint, Mich., is a devastating reminder of how closely human health is intertwined with the environment. While the Flint crisis may
The introduction of screening colonoscopy in Germany is showing results: Within ten years of the start of this screening program for the early detection of
Taking the stairs is normally associated with keeping your body strong and healthy. But new research shows that it improves your brain’s health too —
Strange things happen at night, especially when we’re not sleeping. Results from observational studies of people who don’t sleep much (blue icons) and from experiments
The evidence continues to mount over the importance of the human microbiome—especially within the intestinal tract—for supporting optimal growth and overall health and wellness. Over
Economic booms and improved transportation may come with a costly downside: increased transmission of viral diseases. Adda studied 25 years of weekly disease surveillance reports
Researchers from University of California, Santa Barbara and UCLA report that millions of Americans labeled overweight or obese based on their body mass index (BMI)
Babies born by Cesarean section (C-section) are not always exposed to bacteria and other microbes present in the birth canals of their mothers, a factor
Gorging oneself on high-calorie food to pack on fat only to fall asleep for a few months and have it all melt away isn’t the
Are you the type of person that jumps out of bed bright-eyed and ready to take on the world? If so, your early morning cheeriness
A new study from the Monell Center, the U.S. Department of Agriculture (USDA), and collaborating institutions reports a uniquely identifiable odor signature from mouse models
A new study from the Monell Center, the U.S. Department of Agriculture (USDA), and collaborating institutions reports a uniquely identifiable odor signature from mouse models
Obese individuals have increased circulating levels of inflammatory cytokines produced by adipose tissue macrophages. Velmurugan et al. found that adipose tissue macrophages from obese mice
Plasmodium falciparum antigens expressed on the surface of infected erythrocytes are important targets of naturally acquired immunity against malaria, but their high number and variability
Imaging Life-science imaging broke barriers this year, as scientists built upon microscopy approaches to peer ever deeper into living tissues. In October, Purdue University’s Ji-Xin
A team led by researchers from the University of Copenhagen discovered differences in the sperm epigenomes of lean and obese men, and in the sperm
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