Coronavirus Disguises Its mRNAs Using a Cap-Modifying Enzyme
The mRNAs expressed by SARS-CoV-2 can pass as human mRNAs without too much difficulty. All the viral mRNAs have to do is modify the cap
The mRNAs expressed by SARS-CoV-2 can pass as human mRNAs without too much difficulty. All the viral mRNAs have to do is modify the cap
Studies of blood samples from four rheumatoid arthritis patients collected over years has led to the discovery of an RNA profile that predicts an imminent
In May, researchers showed that people with mild forms of COVID-19, the disease caused by the SARS-CoV-2 virus, have circulating T cells that respond to the
In late December 2019, reports emerged of a mysterious pneumonia in Wuhan, China, a city of 11 million people in the southeastern province of Hubei.
With no ideal animal model that mimics how SARS-CoV-2 infection leads to COVID-19 in people, several research groups are turning to mini-organs grown from human
Drugs that can ‘reprogramme’ immune cells from protecting cancer to attacking it could be an effective new treatment for some men with advanced prostate cancer,
The first cases were reported in Guizhou province in southwestern China in 1956. By February 1957, the disease, a form of influenza that caused typical
On January 9 of this year, Chinese state media reported that a team of researchers led by Xu Jianguo had identified the pathogen behind a mysterious outbreak
Thanks to a remarkable feat of natural molecular engineering that allows our bodies to generate countless different kinds of antibodies against pathogens, COVID-19 survivors typically
Moderna released positive preliminary data of its Phase I trail for COVID-19 vaccine candidate mRNA-1273 yesterday and will progress it into Phase II and Phase
When the Black Death arrived in London by January 1349, the city had been waiting with dread for months. Londoners had heard reports of devastation
For some COVID-19 patients, the body’s immune response may be as destructive as the virus that causes the disease. The persistent high fevers, severe respiratory
Lying in bed on the night of 10 January, scrolling through news on his smartphone, Andrew Mesecar got an alert. He sat up. It was
Highlights •Measuring immunity to SARS-CoV-2 is key for understanding COVID19 and vaccine development •Epitope pools detect CD4+ and CD8+ T cells in 100 and 70% of convalescent
Using tiny brainlike structures grown in a lab dish, researchers have found new evidence that a common virus responsible for cold sores might also be a
Immune warriors known as T cells help us fight some viruses, but their importance for battling SARS-CoV-2, the virus that causes COVID-19, has been unclear.
One of the oldest vaccines could protect us against our newest infectious disease, COVID-19. The vaccine has been given to babies to protect them against
Like so many countries, Iceland, with its population of 364,000 inhabitants, has been stricken by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). From 13 January
Highlights •The spike protein of SARS-CoV-2 harbors a multibasic S1/S2 site •The host cell protease furin cleaves the SARS-CoV-2 spike protein at the S1/S2 site
How SARS-CoV-2 binds to human cells Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of
Abstract Dendritic cells play a key role in the orchestration of antitumor immune responses. The cDC1 (conventional dendritic cell 1) subset has been shown to
Abstract A coronavirus (HCoV-19) has caused the novel coronavirus disease (COVID-19) outbreak in Wuhan, China. Preventing and reversing the cytokine storm may be the key
Abstract We identified seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory illness. Surgical face
The renin–angiotensin–aldosterone system (RAAS) is an elegant cascade of vasoactive peptides that orchestrate key processes in human physiology. Severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1)
Abstract Emerging viral infections are difficult to control because heterogeneous members periodically cycle in and out of humans and zoonotic hosts, complicating the development of
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