Force matters in hospital-acquired infections
Bacterial pathogens show a remarkable capacity to stick to host tissues and implanted biomaterials, grow, and form biofilms on these surfaces (1). These multicellular communities
Bacterial pathogens show a remarkable capacity to stick to host tissues and implanted biomaterials, grow, and form biofilms on these surfaces (1). These multicellular communities
In 2014, Miriam van Staveren went on holiday to the Canary Islands and caught an infection. Her ear and sinuses throbbed, so she went to
Understanding the appropriate balance of “good” bacteria within the intestinal tract has been the focus of much ongoing research for a number of years. Links
Researchers at Emory Health Sciences have detected “heteroresistance” to colistin, a last-resort antibiotic, in already highly resistant Klebsiella pneumoniae. Their study (“Carbapenem-Resistant Klebsiella pneumoniae Exhibiting
A strain of Staphylococcus epidermis found on human skin contains a chemical with cancer-fighting abilities, according to a study published yesterday (February 28) in Science
Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have
Highlights •In contrast to animals, how bacteria behave during combat is poorly understood •Escherichia coli use diverse strategies when attacking opponents with colicin toxins •Cells
Unravel a bacterial survival strategy that they term “density-dependent persistence” or DDP. The authors demonstrate that the majority of isogenic cells in bacterial populations survive
Tuberculosis is no longer on the LAM Lipoarabinomannan (LAM) is a component of the cell wall shed by Mycobacterium tuberculosis, the bacteria responsible for tuberculosis,
A century after they were discovered killing diarrhea-causing bacteria in the feces of World War I soldiers, the viruses known as bacteriophages, or simply phages,
Scientists at NYU Langone Health’s Perlmutter Cancer Center say that at least three kinds of bacteria in the mouths of Americans may heighten or lower
In the past week, public health officials in Madagascar have reported 230 new cases of plague and 17 deaths from the bacterial disease, bringing the
Numerous microorganisms, including bacteria, colonize the intestine where they play important roles in maintaining homeostasis. However, commensal bacteria with pathogenic potential, such as Helicobacter hepaticus,
A team of molecular microbiologists used quantum dot technology to increase the efficacy of antibiotics to the point where they became capable of killing strains
Abstract Streptococcus mutans employs a key virulence factor, three glucosyltransferase (GtfBCD) enzymes to establish cariogenic biofilms. Therefore, the inhibition of GtfBCD would provide anti-virulence therapeutics.
Resurrecting ancient proteins in modern E. coli can protect the bacterium from viral infection, scientists reported today (May 9) in Cell Reports. Researchers from Spain
Some pathogens block generation of reactive oxygen species to evade neutrophil killing, but how that is accomplished is poorly understood. In this issue of Cell
Emerging evidence indicates that the immune system can influence microbiome composition. Chen et al. now report that patients with active ulcerative colitis have low expression
Resistance on a background of tolerance Bacteria survive antibiotic exposure either because they are quiescent when antibiotics are around in the highest concentrations (i.e., tolerance)
Bacteria use two strategies to avoid being killed by antibiotics: resistance and tolerance. Resistance mechanisms such as destruction of a drug or modification of its
Prions enter another domain of life Prions are self-propagating protein aggregates, discovered in connection with the fatal transmissible spongiform encephalopathies in mammals. Prions have also
Microbes use a number of CRISPR-Cas systems for immunity, but it’s the class 2 system, typically utilizing the nuclease Cas9, that has been adapted for
BACKGROUND The escalating crisis of multidrug resistance is raising fears of untreatable infections caused by bacterial “superbugs.” However, many patients already suffer from infections that
Modern agriculture relies on antibiotics to shield livestock from disease, but widespread over-use of antibiotics has raised concerns over creating highly resistant “superbugs.” Researchers announced
While political scenarios facing the world have many people nervous about what kind of future we face, there is a microscopic war that is constantly
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