Study Finds No Neurogenesis in Adult Humans’ Hippocampi
New neurons may not develop in the adult human brain as neuroscientists for years have come to believe. Researchers studying postmortem brain tissue of humans
New neurons may not develop in the adult human brain as neuroscientists for years have come to believe. Researchers studying postmortem brain tissue of humans
Psychiatric disorders display common patterns of gene expression, according to a study published today (February 8, 2018) in Science. Researchers have analyzed transcripts within the
Researchers in Japan and Australia have developed the first blood test to detect amyloid-β protein buildup in the brain, one of the earliest hallmarks of
Centuries ago, humans believed that seizures were tied to the lunar cycle. Although scientific evidence for this association is scarce, physicians have long suspected that
The blood–brain barrier (BBB) keeps neurotoxic plasma-derived components, cells, and pathogens out of the brain. An early BBB breakdown and/or dysfunction have been shown in
A small clinical trial testing the safety of administering young people’s blood plasma to treat Alzheimer’s disease has found that the approach may slightly improve
Alzheimer’s disease may move, cancer like, from place to place in the body, lodging in the brain after originating in peripheral tissues. Just how much
Interneurons in the brain that use GABA (γ-aminobutyric acid) as a neurotransmitter are essential for functional circuits. During development, these interneurons migrate tangentially from their
Circular RNAs (circRNAs) have attracted growing attention in recent years, but their function in living organisms has long remained a mystery. Now, researchers report that
In this issue of Cancer Cell, Saha et al. systematically test and optimize combination therapy strategies in a challenging model of glioblastoma. Durable complete responses
Early phase Northwestern Medicine research published in the journal Proceedings of the National Academy of Sciences has demonstrated a potential new therapeutic strategy for treating
Microglia are phagocytic cells that remove cellular debris and aggregated proteins from the brain and prune unwanted and degenerating synapses (1). When the brain is
Microglia are phagocytic cells that remove cellular debris and aggregated proteins from the brain and prune unwanted and degenerating synapses (1). When the brain is
In this issue of JEM, Marciniak et al. (https://doi.org/10.1084/jem.20161731) identify a putative novel function of tau protein as a regulator of insulin signaling in the
A 21-million-image dataset of the female fruit fly brain is offering an unprecedented view of the cells and their connections that underlie the animal’s behavior.
In the postnatal mammalian brain, neurons continue to be generated and migrate to their home stations. Often, these neuroblasts travel along pathways defined by the
Advancing age predisposes us to a number of neurodegenerative diseases, yet the underlying mechanisms are poorly understood. With some 70 million individuals affected, glaucoma is
The human cerebral cortex experiences a burst of growth late in fetal development thanks to the expansion and migration of progenitor cells that ultimately form
A unique human ability is the use of concepts that confer meaning in an abstract way. Despite the importance of conceptual knowledge for human cognition,
In more than three dozen postmortem human brains, scientists have detected nanoparticles of magnetite that they suspect came from the environment. The brain produces magnetite
Neurons within a single brain can differ from one another in genomic content—a phenomenon known as mosaicism. But the extent to which those differences are
A dietary supplement containing a blend of thirty vitamins and minerals–all natural ingredients widely available in health food stores–has shown remarkable anti-aging properties that can
Plaques of amyloid-β peptides in certain parts of the brain are a telltale sign of Alzheimer’s disease–associated neurodegeneration. When not in pathological aggregates, these peptides—found
A new study jointly led by the University of Southampton and King’s College London has found a link between gum disease and greater rates of
Taking the stairs is normally associated with keeping your body strong and healthy. But new research shows that it improves your brain’s health too —
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