Russian ‘CRISPR-baby’ scientist has started editing genes in human eggs with goal of altering deaf gene
Russian biologist Denis Rebrikov has started gene editing in eggs donated by women who can hear to learn how to allow some deaf couples to
Russian biologist Denis Rebrikov has started gene editing in eggs donated by women who can hear to learn how to allow some deaf couples to
Preliminary research suggests that using CRISPR to treat cancer is safe in humans and could become a feasible therapeutic method in the future, although its
A new gene editing technique called prime editing, tested in human and mouse cells, rewrites DNA by only cutting a single strand to add, remove,
A study published in Nature Medicine that found an increased mortality rate in people with an HIV-preventing gene variant has a major flaw, according to
The failure of drugs that seemed promising in laboratory tests to prove themselves in human testing is an all-too-common occurrence, dashing hopes and costing billions
Imagine a word processor that allowed you to change letters or words but balked when you tried to cut or rearrange whole paragraphs. Biologists have
his story introduces Science’s CRISPR in China series, supported by the Pulitzer Center. For many people, CRISPR plus China equals the biophysicist He Jiankui, who
People with a rare form of inherited blindness are being enrolled for the world’s first in vivo study of a CRISPR-based therapy, the Associated Press
Searching a sample of DNA for a particular sequence—be it a mutation, a researcher-inserted transgene, or evidence of an infecting organism—is a common practice in
Last month, the US Patent and Trademark Office reignited the infamous CRISPR patent dispute when it declared interference—overlapping intellectual property—between several pending patents belonging to
Senators Dianne Feinstein (D-CA), Marco Rubio (R-FL), and Jack Reed (D-RI) introduced a resolution yesterday (July 15) calling for global collaboration in developing guidelines for
Vaccines prevent millions of deaths a year and have pushed some diseases to the edge of existence. Yet it’s proven highly challenging, if not impossible,
There should be a global moratorium on editing heritable DNA from humans, scientists and bioethicists from seven countries write today (March 13) in a Nature
The paper I. Turgeman-Grott et al., “Pervasive acquisition of CRISPR memory driven by inter-species mating of archaea can limit gene transfer and influence speciation,” Nat
The world’s first gene-edited babies were announced early this week not in a scientific publication or at a conference, but in news reports. He Jiankui,
For the past few decades, it has been possible to directly manipulate an organism’s genes early in development, to generate, for example, mice that harbour
A therapy that edits genes directly in the human body might be safe, suggest early findings from the first trial to test the approach. Researchers
Two studies published yesterday (October 9) in Nature Medicine report success using modified CRISPR-Cas9 gene editing to prevent or cure two inherited diseases in mice.
A consortium of 17 laboratories worldwide has presented results contradicting a highly cited study that described a technique to create conditional knockout mice using CRISPR.
Newly identified anti-CRISPR proteins block Cas12a, a cousin of the Cas9 nuclease, both of which are widely used in genome editing, two teams of researchers
CRISPR, the genome-editing tool, introduced a mutation in a dog gene that, in effect, overrode a mutation responsible for a disease that mimics Duchenne muscular
Researchers hope to develop treatments for a wide range of genetic disorders, and even cancer, using CRISPR-Cas9 gene editing. These clinical interventions may take the
Using CRISPR, researchers have crafted a technique to study mammalian development in exceptional detail, according to a report published in Science yesterday (August 9). “This
CRISPR gene editing can create large numbers of unwanted DNA changes that may go undetected, researchers report today (July 16) in Nature Biotechnology. The findings
Bacteria can fend off viral infections by chopping up their DNA with their CRISPR-based immune system, but sufficient numbers of phages can overwhelm microbes’ defenses.
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