NIH Announces Details of Human Fetal Tissue Research Restrictions
Last Friday (July 26), the National Institutes of Health announced new restrictions on human fetal tissue research for scientists applying for grants using the material
Last Friday (July 26), the National Institutes of Health announced new restrictions on human fetal tissue research for scientists applying for grants using the material
The cells that circulate in the bloodstream perform various functions and, in adults, are derived from progenitor cells in the bone marrow. Mutations in the
An imaging technique that uses chemical reactions instead of light can reveal the spatial organization and sequences of DNA molecules inside cells. Joshua Weinstein at
A newly developed method called DNA microscopy can accurately pinpoint the location of mRNA molecules within a cell and produce a visual map of the
Fetal DNA that is circulating in the blood of pregnant women is frequently extracted noninvasively and screened for common chromosome aneuploidies that cause disease such
The DNA of life on Earth naturally stores its information in just four key chemicals — guanine, cytosine, adenine and thymine, commonly referred to as
A person’s sex can affect the kinds of cancer-causing mutations they develop, according to a genomic analysis spanning nearly 2,000 tumours and 28 types of
Introns are short stretches of non-coding DNA interspersed with the coding DNA in the genes of eukaryotic organisms. They are widespread and common but their
Patches of seemingly meaningless DNA dotted throughout the genome might actually have a function: helping cells to survive starvation. Two studies published in Nature on
Typically, humans inherit mitochondria and mitochondrial DNA from their mothers only. But using sequencing data from the mitochondrial genomes of members from three unrelated families,
In the mid-1800s, Lionel Smith Beale, an English physician and microscopist at King’s College in London, peered through his microscope at a smear of saliva
Gene therapy generally relies on delivering DNA into cells along with strategies to control its expression. Synthetic messenger RNA (mRNA) is an attractive alternative gene
Japan has issued draft guidelines that allow the use of gene-editing tools in human embryos. The proposal was released by an expert panel representing the
Newly identified anti-CRISPR proteins block Cas12a, a cousin of the Cas9 nuclease, both of which are widely used in genome editing, two teams of researchers
Scientists at Hollings Cancer Center at the Medical University of South Carolina have found that some cells can divide without a molecule that was previously
Multiple myeloma (MM) is a biologically heterogeneous malignancy, however, the mechanisms underlying this complexity are incompletely understood. We report an analysis of the whole-genome sequencing
Stroke is the second leading cause of death worldwide, but the molecular mechanisms underlying the condition are poorly understood. Now, an international team of researchers
CRISPR-Cas9 cleaves DNA, enabling genome editing. Surprisingly, three studies have concurrently uncovered an intrinsic RNA cutting activity of Cas9. Cas9 cuts endogenous RNA in some
A strain of Staphylococcus epidermis found on human skin contains a chemical with cancer-fighting abilities, according to a study published yesterday (February 28) in Science
Camelids such as camels, llamas, and alpacas make an unusual class of antibodies with a growing number of applications in biomedical science. But researchers wanting
Structure of the human spliceosome Catalyzed by the spliceosome, precursor mRNA splicing proceeds in two steps: branching and exon ligation. Transition from the C (catalytic
In the nematode worm Caenorhabditis elegans, as in humans, offspring inherit mitochondria and mitochondrial DNA only from their mother. Sato et al. identified key molecular
Cell cycle events are precisely orchestrated to ensure accurate cell division. Yang et al. have discovered that sequestering mature mRNAs in the nucleus modulates cell
A research team headed by scientists at Johns Hopkins Kimmel Cancer Center has developed a multianalyte blood test that can screen for eight common forms
nfection with the parasite Plasmodium falciparum causes malaria. Individuals may be infected with multiple strains of P. falciparum, some of which may be drug-resistant. Understanding
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