“Expand your mind, man!” was a popular phrase that arose from the 1960’s counterculture movement. However, it was most likely not referring to the specific
Cancer researchers have are warning drug developers that in about 62% of ovarian cancer cell samples levels of messenger RNA and protein did not accurately
Gut microbes possibly influence not only the development of many human diseases, but also how these diseases respond to treatment. In tumor models, for example,
The development of oral insulin-sensitizing agents to minimize the need for injectable insulin remains a major unmet need in the treatment of diabetes. Now, writing
A new treatment strategy has had astonishing success against extensively drug-resistant tuberculosis (XDR TB), which kills more than 70% of patients. XDR and other drug-resistant
The spiraling cost of new drugs mandates a fundamentally different approach to keep lifesaving therapies affordable for cancer patients. We call here for the formation of
On 26 January, Ling Wang and Qinzi Xu, two biomedical scientists at the University of Pittsburgh in Pennsylvania, placed a mouse under a chemical hood,
Chronic myelogenous leukemia (CML) is caused by chromosomal translocation that creates a fused gene; this gene produces an oncoprotein, BCR-ABL. Targeting this protein with imatinib
Mouse models do not fully capture the degeneration of brain networks seen in human Alzheimer’s disease (AD). Thus, extensive validation of therapeutic targets in many
Mouse models do not fully capture the degeneration of brain networks seen in human Alzheimer’s disease (AD). Thus, extensive validation of therapeutic targets in many
Methicillin-resistant Staphylococcus aureus (MRSA) is a worldwide threat to human health, because it is resistant to a large class of β-lactams (penicillins) and to second-generation
Researchers at the pharmaceutical company Merck have identified a new bacteria-killing compound with an unusual target—an RNA regulatory structure called a riboswitch. The team used
A synthetic DNA–based vaccine targeting the Middle East respiratory syndrome coronavirus (MERS-CoV) protects rhesus macaques from developing symptoms of the disease. The vaccine also elicits
A magnetic blood filtering device is under development by start-up company MediSieve to capture and remove red blood cells infected with drug resistant malaria. The
Move over, poppies. In one of the most elaborate feats of synthetic bio logy to date, a research team has engineered yeast with a medley
At first glance, SPRITAM looks like any other pill. But the drug, developed by pharmaceutical company Aprecia, is actually layers of powder laid down by
After years of disappointment, clinical-trial results released on 22 July suggest that antibody treatments may produce small improvements in people with Alzheimer’s disease. The drugs
Researchers from Singapore‘s Nanyang Technological University (NTU), McLean Hospital, andHarvard Medical School report that they have found that existing anti- malaria drugs could be a
Treatment directed at a newly identified drug target in rheumatoid arthritis (RA) would prevent damage to the joints while not increasing the immune suppression that
Scientists at the University of Waterloo in Canada report that a new family of molecules that kill cancer cells while protecting healthy cells could be
A company that has spent more than 20 years trying to develop treatments based on embryonic stem cells is taking encouragement from small, preliminary tests
An article published earlier this month on the website of the European Heart Journal claimed that European guidelines on the use of β blockers in surgery patients
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