Smoking-Linked Cancer Mutations Mapped
Researchers have uncovered the genomic mutations and DNA methylation patterns likely caused by tobacco smoke in 17 types of cancerous tumors. A comprehensive survey of
Researchers have uncovered the genomic mutations and DNA methylation patterns likely caused by tobacco smoke in 17 types of cancerous tumors. A comprehensive survey of
Before we understood that DNA was the genetic code, scientists knew that bacteria transferred it between cells. In 1928, 25 years before the structure of
Demonstrating yet another basic research application of CRISPR, two teams have independently reported scaled up CRISPR interference (CRISPRi) and CRISPR/Cas9 noncoding genomic screens. Researchers at MIT
For the past 2 years, the National Cancer Institute (NCI), the University of Chicago, the Ontario Institute for Cancer Research, and Leidos Biomedical Research have
Each newly-formed T cell bears a unique T cell receptor (TCR) that recognizes a particular antigen. But how a given TCR shapes the fate of
Most genomic studies to date have focused on linking mutations to diseases. Taking a new approach, researchers studying the genomes of apparently healthy individuals identified
Last year, Elizabeth Parrish, the CEO of Seattle-based biotech firm BioViva, hopped a plane to Colombia, where she received multiple injections of two experimental gene
In 2010 the J. Craig Venter Institute (JCVI) shocked the scientific world by creating the first synthetic cell,Mycoplasma mycoides JCVI-syn1.0, which contained slightly over 1
n the last decade or so, researchers have spent billions of dollars categorizing the microbes that populate sites as disparate as the human body, soil,
A team of researchers at the Gladstone Institutes in San Francisco, California, has used a version of CRISPR gene editing known as CRISPR interference (CRISPRi) to
Dozens of genetic mutations are known to facilitate cancer progression, but metastasis doesn’t appear to be controlled by additional changes to the genome. A study
In the depths of February, many people living in wintry northern climes find themselves bummed out and craving the sunny days of summer. Now, researchers
In cells undergoing senescence, chromosomes tend to become more compact, according to a report published today (February 5) in Science Advances.This and other chromatin rearrangements
The allele apolipoprotein E ε4 (APOE ε4) is the greatest genetic risk factor for Alzheimer’s disease (AD), but the role of the ApoE4 protein in
If it’s seven o’clock on an August morning, I can pretty much guarantee you this is what’s going on at my house: I open my
If it’s seven o’clock on an August morning, I can pretty much guarantee you this is what’s going on at my house: I open my
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