Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
How SARS-CoV-2 binds to human cells Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of
How SARS-CoV-2 binds to human cells Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of
Abstract Emerging viral infections are difficult to control because heterogeneous members periodically cycle in and out of humans and zoonotic hosts, complicating the development of
A novel human coronavirus that is now named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (formerly called HCoV-19) emerged in Wuhan, China, in late 2019
Abstract Vascularized composite allotransplantation (VCA) encompasses face and limb transplantation, but as with organ transplantation, it requires lifelong regimens of immunosuppressive drugs to prevent rejection.
The Center for Systems Science and Engineering (CSSE) at Johns Hopkins University developed a real time mapping of the corona virus. Covid-19 outbreak is now
PAX1 in the thymus Severe combined immunodeficiency (SCID) encompasses a wide spectrum of genetic disorders. Here, Yamazaki et al. have studied immune deficits in six
CRISPR takes first steps in humans CRISPR-Cas9 is a revolutionary gene-editing technology that offers the potential to treat diseases such as cancer, but the effects
More than 50 research papers have been published on the new Chinese coronavirus in the past 20 days, as scientists rush to understand the pathogen
Immune cells altered by CRISPR are safe to use in cancer patients, according to results of a clinical trial reported today (February 6) in Science.
A novel type of killer T cell has been identified as a potential universal cancer therapy. The most widely used T-cell therapy, CAR T, is
Researchers at the University of Washington have discovered a novel DNA-sensing pathway that launches an antiviral response to foreign genetic material in human cells. Triggered
There are a lot of unknowns when it comes to understanding how the mammalian respiratory tract responds to allergens, but a study published today (January
About four years ago, pathologist Matthew Anderson was examining slices of postmortem brain tissue from an individual with autism under a microscope when he noticed
Highlights • BFD1 is a master regulator of chronic-stage differentiation in Toxoplasma gondii • ΔBFD1 parasites fail to differentiate in cell culture or form cysts
Discovery of a new T cell With all the extensive investigations scientists have conducted of the human immune system over the past century, it is
Cell therapies to treat cardiac damage have been moving through clinical trials, with mixed results. Often, stem cells are taken from a patient’s bone marrow
The world finally has an Ebola vaccine. On 11 November, European regulators approved a vaccine that has already helped to control deadly outbreaks of the
Autoimmune diseases tend to ease up during pregnancy, and for women with multiple sclerosis, physicians have documented fewer relapses of the condition while women are
Mice fed a ketogenic diet—in which 90 percent of calories come from fat and less than 1 percent from carbohydrates—were less susceptible to the influenza
Koalas are susceptible to cancers such as lymphoma and leukemia along with chlamydia infections due to koala retrovirus, a pathogen that began inserting itself into
In the early 2000s, Arturo Zychlinsky at the Max Planck Institute for Infection Biology in Berlin found that mammalian immune cells called neutrophils use an
Chikungunya virus (CHIKV) is a re-emerging alphavirus that is transmitted to humans by mosquito bites and causes musculoskeletal and joint pain1,2. Despite intensive investigations, the
Mounting evidence in animal models, as well as correlative studies in humans, indicate that the microbes present in the gut can shape immune responses. In
An effective immune response to general signs of infection, regulated by the branch of the immune system called innate immunity, is essential for the removal
Scientists extracted a near-complete HIV-1 genome from a lymph node that had been preserved in wax for more than 50 years. The sample stands as
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