Immune Cell Bank Bets on Future CAR T Success
A new cryopreservation bank offers customers the chance to stash away their T cells for use in future cancer treatments. Using a similar model to
A new cryopreservation bank offers customers the chance to stash away their T cells for use in future cancer treatments. Using a similar model to
For years, scientists thought the brain lacked a lymphatic system, raising questions about how fluid, macromolecules, and immune cells escape the organ. In 2015, two
Immunoglobulin G (IgG) has been pinpointed as the likely culprit in hitherto unexplained cases of dangerous immune reactions known as anaphylaxis in response to anesthetic
Every day, billions of our cells die quietly and in an orderly fashion by activating a cell suicide program known as apoptosis. But others, often
Inflammation can help to eliminate infection, but excessive inflammation can cause damage to the body. The sensor proteins that trigger an inflammatory immune response must
A child in Uganda has been diagnosed with Ebola — marking the first confirmed case in the country since an outbreak of the virus emerged
A study published today (June 3) in Nature Medicine confirms previous reports that a variant of the gene CCR5 that protects against infection by HIV
Broadly neutralizing monoclonal antibodies protect against infection with HIV-1 in animal models, suggesting that a vaccine that elicits these antibodies would be protective in humans.
According to textbooks, cells of the adaptive immune system must be either B cells or T cells—they can’t be both, or anything in between. But
Towards the final stages of diseases such as cancer and kidney disease, many patients develop cachexia, a devastating condition in which muscle mass and fat
Vaccines prevent millions of deaths a year and have pushed some diseases to the edge of existence. Yet it’s proven highly challenging, if not impossible,
Genetically modified viruses have successfully treated an antibiotic-resistant infection in a teenage girl, saving her life, researchers report today (May 8) in Nature Medicine. While
scientists have long believed that humans and many other mammals have two types of immune systems: innate and adaptive. The former is driven by natural
By tweaking the chimeric antigen receptor or CAR engineered into T cells to treat patients’ lymphoma, scientists have avoided side effects common to the immunotherapy,
A bacterium which is responsible for about 10% of hospital-acquired infections in the US uses a virus to trick a person’s immune system into ignoring
Zika virus (ZIKV) was discovered in Africa in 1947. Its impact on public health seemed restricted to sporadic local outbreaks associated with an illness characterized
For the second time, a person living with HIV appears to have cleared the virus after a stem cell transplant replaced his infected immune cells
The mosquito-borne Zika virus that recently spread rapidly throughout the Americas shares many characteristics with another virus: dengue. Both are flaviviruses, which are enveloped, sphere-shape
lthough CAR T cells have made their claim to fame in treating leukemia and lymphoma, scientists have now shown they can be directed toward other
Over the past 50 years, the frequency of allergies and autoimmune diseases has risen rapidly, but it’s not clear why. In a study published today
Previous studies have found that a warming climate may change the distribution of different diseases and the insects that carry them. Now, a new study
While scientists have evidence that the composition of the gut microbiome is connected to a variety of autoimmune diseases, understanding how bugs in the intestine
Traces of the bacterium Porphyromonas gingivalis, which causes chronic gum disease, have been found in the brains of people who had Alzheimer’s disease. The result
Instructing the immune system to recognize and kill tumours, an approach termed cancer immunotherapy, has transformed the clinical treatment of certain types of malignancy. Prominent
The influenza virus mutates constantly, and work1 published this month on bioRxiv reveals that this viral volatility can affect whether, and how, a host cell
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