Scientists from Fred Hutchinson Cancer Research reported data from an early-phase study of patients with advanced non-Hodgkin’s lymphoma (NHL) who received JCAR014, a chimeric antigen
Oncologist You Lu of Sichuan University’s West China Hospital in Chengdu and colleagues will soon begin trialing a new CRISPR-based immunotherapy in 10 patients with
Following genetically marked donor memory T cells infused into hematopoietic stem cell transplantation patients, a team led by researchers at the University Vita-Salute San Raffaele
A London baby with end-stage leukemia has received a remarkable new cancer treatment: off-the shelf T cells with several gene modifications. Doctors say it’s too
A London baby with end-stage leukemia has received a remarkable new cancer treatment: off-the shelf T cells with several gene modifications. Doctors say it’s too
Although best known for their pathogen-fighting prowess, T lymphocytes also ensure that the immune response does not run amok. A subset of T cells called
Scientists at UC Davis have found that early exposure to inflammatory cytokines, such as interleukin 2, can stymie the activity of CD4 T cells, immune
Patients with advanced melanoma can survive longer after treatment with the immunotherapy drug ipilimumab. Kvistborg et al. show how this therapeutic antibody exerts its beneficial effects. Although
Therapeutic transfer of virus-specific T cells to immunocompromised patients can help battle life-threatening infections, but the process for generating such cells is lengthy and laborious.
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