Mother’s Microbiome Shapes Offspring’s Immunity
Pregnant mice expose their unborn pups to maternal gut microbes, which can affect the development of the innate immune system after birth, according to a
Pregnant mice expose their unborn pups to maternal gut microbes, which can affect the development of the innate immune system after birth, according to a
Myc, a transcriptional regulator that is overexpressed in several human cancers, appears to have a direct role in preventing immune cells from efficiently attacking tumor
There is a growing reproducibility problem across the life sciences. The retraction rate of published papers has increased tenfold over the past decade, and researchers
From blood samples of survivors of a 2007 Ebola outbreak in Uganda, researchers have isolated antibodies that are protective and can neutralize two other species
Since it was discovered in 2012, the camel-borne virus causing Middle East respiratory syndrome (MERS) has sickened more than 1200 people in the Middle East
Gut microbes have ascended to prominence as key modulators of host immunity, raising the possibility that they could influence the outcome of cancer immunotherapy. Two
If it’s seven o’clock on an August morning, I can pretty much guarantee you this is what’s going on at my house: I open my
If it’s seven o’clock on an August morning, I can pretty much guarantee you this is what’s going on at my house: I open my
Following genetically marked donor memory T cells infused into hematopoietic stem cell transplantation patients, a team led by researchers at the University Vita-Salute San Raffaele
A London baby with end-stage leukemia has received a remarkable new cancer treatment: off-the shelf T cells with several gene modifications. Doctors say it’s too
A London baby with end-stage leukemia has received a remarkable new cancer treatment: off-the shelf T cells with several gene modifications. Doctors say it’s too
T cell infiltration of solid tumors is associated with favorable patient outcomes, yet the mechanisms underlying variable immune responses between individuals are not well understood.
Immunologists from Trinity College in Dublin say they have unearthed a key piece of the MRSA vaccine puzzle by identifying specific T-helper cells whose role
In anticancer campaigns, the immune system has often shown too little fighting spirit. It can be too civilized, too restrained unless it is specially outfitted
For many complex diseases, a mix of a person’s genes and their environment determines their susceptibility, with genetic influences often playing a greater role in
Researchers in Australia added an adjuvant to an inactivated influenza A vaccine and successfully boosted the shot’s effectiveness and cross-protective capabilities, according to a study
Precision medicine is all about the two T’s—targets and treatments—targets that emerge from analyses of patient-specific information, and treatments that hit these targets. Both T’s,
Although best known for their pathogen-fighting prowess, T lymphocytes also ensure that the immune response does not run amok. A subset of T cells called
Researchers say that they have found a way to smuggle drug-carrying nanoparticles past the body’s immune system: by camouflaging them to look like cell fragments
Researchers say that they have found a way to smuggle drug-carrying nanoparticles past the body’s immune system: by camouflaging them to look like cell fragments
To understand whether the human skin microbiome can affect the ability of a bacterial pathogen to cause an infection, researchers have had to rely on observational
Part of the innate immune system, white blood cells called neutrophils circulate in the blood and are the first responders to an influenza respiratory infection,
For HIV to develop into full-blown AIDS, the virus must deplete a subset of immune cells called CD4+ T cells, disabling an infected person’s adaptive
The candidate drug daratumumab, which is a monoclonal antibody that targets the cell surface molecule CD38 (cluster of differentiation 38), was shown to be a
It sounds paradoxical, but chimeric antigen receptor (CAR) T cells can be more easy-going and more effective at killing cancer cells. Engineering a lackadaisical but
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