Lowering the Levels of Key Protein Might Be a Novel Way To Treat MS
In an animal model of multiple sclerosis (MS), decreasing the amount of a protein made in the liver significantly protected against development of the disease’s
In an animal model of multiple sclerosis (MS), decreasing the amount of a protein made in the liver significantly protected against development of the disease’s
The endogenous compound anandamide – often referred to as the body’s own marijuana – plays a role in erasing memories of a traumatic event. This
Ultrasound and microbubbles can safely open the blood-brain barrier in patients with Alzheimer’s disease, researchers reported yesterday (July 25) in Nature Communications and at the
Researchers at Caltech have designed a noninvasive method to control specific neural circuits in the mouse brain. The technique, published earlier this week (July 9)
The tuberal nucleus, an area of the hypothalamus, has not been studied in great detail.Luo et al. found that GABAergic somatostatin neurons in the tuberal
In the suprachiasmatic nucleus, the brain’s central pacemaker, CLOCK (circadian locomotor output cycles kaput) is a transcription factor that plays a crucial role in regulating
In 2015, the global cost of Alzheimer’s disease was US$818 billion. That’s similar to the gross domestic product of the world’s 18th-largest economy. By 2030,
Interneurons in the brain that use GABA (γ-aminobutyric acid) as a neurotransmitter are essential for functional circuits. During development, these interneurons migrate tangentially from their
Like many humans, non-human primates deposit copious misfolded Aβ protein in the brain as they age. Nevertheless, the complete behavioral and pathologic phenotype of Alzheimer’s
Cells that prune connections between neurons in babies’ brains as they grow are thought to have a role in autism spectrum disorder. Now, a study
Astrocytes, star-shape glial cells in the brain, were once simply considered support cells for neurons. However, neuroscientists have recently realized they have many other functions:
Many people with Parkinson’s disease have digestive symptoms like constipation years before they have neurological symptoms, and scientists have found differences in the gut microbiome
A study led by biomedical researchers at Indiana University has found evidence that an enzyme known as NMNAT2 may help protect against the debilitating effects
A dietary supplement containing a blend of thirty vitamins and minerals–all natural ingredients widely available in health food stores–has shown remarkable anti-aging properties that can
Plaques of amyloid-β peptides in certain parts of the brain are a telltale sign of Alzheimer’s disease–associated neurodegeneration. When not in pathological aggregates, these peptides—found
When it comes to bedding down in an unfamiliar place, the old adage about sleeping with one eye open may not be that far from
Heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptors (GPCRs) can form multiprotein complexes (heteromers), which can alter the pharmacology and functions of the constituent receptors. Previous
A well-powered clinical trial that failed to replicate promising results in animal models of fragile X syndrome yields important lessons for clinical trial design (Berry-Kravis
To investigate the potential usefulness of artificial bright light in nonseasonal depression, investigators in Canada randomized 122 medication-free patients with moderately severe, nonpsychotic, nonbipolar major
Neuroscientists have developed a method to pick out an individual solely by his connectome a pattern of synchronized neural activity across numerous brain regions. Researchers
For decades, researchers have known that forming memories requires that the expression and translation of some genes be upregulated in the brain. Unexpectedly, the mouse
The hormone leptin, produced by fat cells, acts as a satiety signal to the brain, resulting in fat breakdown when levels are high. The hormone,
The electrical activity of a neuron is considered a fundamental feature of its identity. But new research reveals this attribute is not necessarily fixed, at
Neuroscientists have identified an area of the brain that might give the human mind its unique abilities, including language. The area lit up in human,
Researchers from Singapore‘s Nanyang Technological University (NTU), McLean Hospital, andHarvard Medical School report that they have found that existing anti- malaria drugs could be a
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