Hormone Loss Prevents Obesity and Diabetes in Mice
Two people with a rare genetic disorder have helped shed light on the fundamental neuroscience of appetite and, scientists say, opened up a new target
Two people with a rare genetic disorder have helped shed light on the fundamental neuroscience of appetite and, scientists say, opened up a new target
In the early 2000s, a long-standing problem affecting diabetes sufferers around the world seemed on the brink of being solved. After years of research and
In this issue of JEM, Marciniak et al. (https://doi.org/10.1084/jem.20161731) identify a putative novel function of tau protein as a regulator of insulin signaling in the
The development of oral insulin-sensitizing agents to minimize the need for injectable insulin remains a major unmet need in the treatment of diabetes. Now, writing
Highlights • Fasting mimicking diet induces prenatal-development gene expression in adult pancreas • FMD promotes Ngn3 expression to generate insulin-producing β cells • Cycles of
Islet transplantation is an established therapy for diabetes. We have previously shown that rat pancreata can be created from rat pluripotent stem cells (PSCs) in
Engineering cells to regulate glucose Diabetes mellitus affects hundreds of millions of people worldwide. Blood glucose levels are chronically deregulated in diabetics, and this can
It’s practically dogma at the health food store: Substances called antioxidants, found in foods from blueberries to broccoli, are cancer’s nemesis, and the more you
Diabetics who use the commonly prescribed drug metformin to control blood sugar levels have a different composition of gut microbiota than other diabetics, according to
Sanofi will use technology licensed from Hanmi Pharmaceutical to develop a portfolio of long-acting diabetes treatments. The licensing agreement, announced today, indicates that the technology,
Chronic myelogenous leukemia (CML) is caused by chromosomal translocation that creates a fused gene; this gene produces an oncoprotein, BCR-ABL. Targeting this protein with imatinib
The future of medical sensors may be going down the tubes. Chemists are developing tiny devices made from carbon nanotubes wrapped with polymers to detect
Is consuming sugar-sweetened beverages, artificially sweetened beverages, and fruit juice associated with excess risk for developing type 2 diabetes? To answer this question, researchers performed
Cold exposure may be a potential therapy for diabetes by increasing brown adipose tissue (BAT) mass and activity. Here we report that 10 d of
The device: A patch containing 121 microneedles loaded with specialized nanoparticles designed to release insulin when glucose levels are high could make insulin delivery a
First out is a kidney: its dark red fades to beige as it is washed of its blood. The pancreas, harder to find amid the
A multidisciplinary research team has discovered how cells know to rush to a wound and heal it opening the door to new treatments for diabetes,
A novel concept for treating diabetes was demonstrated by feeding diabetic rats a diet containing human lactobacilli that had been genetically engineered to secrete the
Neurology, August 2, 2011 vol. 77 no. 5 461-468. S. Debette, S. Seshadri, A. Beiser, R. Au, J.J. Himali, C. Palumbo, P.A. Wolf and C.
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