Selective delivery of copper (Cu) to the central nervous system effectively treats the motor neuron disease amyotrophic lateral sclerosis (ALS) in the most widely used
Researchers from University of California, Santa Barbara and UCLA report that millions of Americans labeled overweight or obese based on their body mass index (BMI)
In numerous clinical trials, researchers have injected patients with various types of progenitor cells to help heal injured hearts. In some cases, subjects have ended
Cancer researchers have linked development of resistance to the anticancer drug temozolomide by glioblastoma multiforme (GBM) brain cancer cells to the activity of the RhoG-specific
From blood samples of survivors of a 2007 Ebola outbreak in Uganda, researchers have isolated antibodies that are protective and can neutralize two other species
It’s hard to recall a revolution that has swept biology more swiftly than CRISPR. Just 3 years ago, scientists reported that the CRISPR system an
Mitochondria contain proteins encoded by the nucleus and by their own mitochondrial genome. Sometimes protein synthesis within the mitochondria goes wrong, which can damage both
Doctors wrote 259 million opioid prescriptions for Americans in 2012, enough to medicate every adult in the country. Drug overdoses are eclipsing car crashes as a leading cause of accidental death for
When animals eat, gut bacteria numbers spike. It also appears that the organisms have a means of limiting growth: by sending signals to their host
Several years ago, antiobesity drug development was not looking so hot. In 2007, Sanofi-Aventis failed to win US Food and Drug Administration (FDA) approval for
A commonly prescribed antidepressant exerts epigenetic effects that may provide a useful biomarker of whether the drug works in patients. A team led by researchers
Removing built-up plaques of amyloid-β in the brain is a long-sought therapy for patients with Alzheimer’s disease, but for a variety of reasons, few treatments
T cell infiltration of solid tumors is associated with favorable patient outcomes, yet the mechanisms underlying variable immune responses between individuals are not well understood.
We live in a world flooded with light 24 hours a day. Before our recent harnessing of electricity, light was a reliable indicator of seasonal
Years after Elizabeth Blackburn, Ph.D. won the Nobel Prize for her seminal work on the molecular nature of telomeres and co-discovery of the ribonucleoprotein enzyme
Researchers say that they have found a way to smuggle drug-carrying nanoparticles past the body’s immune system: by camouflaging them to look like cell fragments
Researchers say that they have found a way to smuggle drug-carrying nanoparticles past the body’s immune system: by camouflaging them to look like cell fragments
A revolutionary way of making stem cells claimed last year by Japanese and US researchers never existed in the first place. That is the conclusion
Helicobacter pylori causes stomach ulcers and is linked to gastric cancer. How does this microbe survive in the destructive environment of the stomach? Huang et
Part of the innate immune system, white blood cells called neutrophils circulate in the blood and are the first responders to an influenza respiratory infection,
Is consuming sugar-sweetened beverages, artificially sweetened beverages, and fruit juice associated with excess risk for developing type 2 diabetes? To answer this question, researchers performed
Two embattled California universities are no closer to reaching an amicable end to their disagreement after a superior court judge dealt a win to the
The origins of new fat cells (adipocytes), which we humans must make throughout our lives, have not been clear. Rodent studies have produced conflicting results
The only HIV vaccine to show promising efficacy in clinical trials stimulated an antibody-based defense in some individuals but not in others. Analyzing patients’ samples
KRAS is one of the most frequently mutated oncogenes in human cancer. Despite substantial efforts, no clinically applicable strategy has yet been developed to effectively
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