About four years ago, Jay Tischfield, the director of RUDCR Infinite Biologics, a long-standing biorepository at Rutgers University, found himself sitting on a gold mine. RUDCR
In the process of converting a somatic cell to a stem cell, researchers have questioned whether the resulting cells retain characteristics of their prior, non-stem-cell
Scientists have successfully grown functional skeletal muscle in the lab and, after implanting it into a mouse, have observed the tissue fix itself after an
A Japanese investigating committee concluded that image manipulation and the use of pictures from an old experiment constitute research misconduct in one of two papers reporting a new method of deriving
Current approaches for turning differentiated adult cells back into a stem–cell-like state involve messing with the nucleus in one way or another—either swapping out nuclear
In 2007, Japanese scientist Shinya Yamanaka reprogrammed adult skin cells into a stem-like state using a quartet of genes. These induced pluripotent stem cells (iPSCs)
Liver cells derived from human induced pluripotent stem cells (iPSCs) and cultured with developmentally important progenitor cells self-organize into functional, three-dimensional liver buds, according to
Researchers have coaxed induced pluripotent stem cells (iPSCs) derived from mice to become several different cell lines and transplanted those cells into genetically identical mice
Most children with spinal muscular atrophy (SMA) will never jump rope, play tag, or even walk because a genetic deletion will provoke the gradual destruction
Nature Communications 3, Article number: 608; Doi: 10.1038/ncomms1611 Mitra Lavasani, Andria R. Robinson, Aiping Lu, Minjung Song, Joseph M. Feduska, Bahar Ahani, Jeremy S. Tilstra,
Nature 480, 209-214 (2011); doi:10.1038/nature10649. P. Janich, G. Pascual, A Merlos-Suárez,E. Batlle, J. Ripperger et al. “The circadian molecular clock creates epidermal stem cell heterogeneity”.
Nature 478, 399–403 (2011).Doi:10.1038/nature10525. Benjamin Beck, Gregory Driessens, Steven Goossens, Khalil Kass Youssef, Anna Kuchnio et al. “A vascular niche and a VEGF–Nrp1 loop regulate
PLoS ONE, July 15, 2011; 6 (7): e21463 DOI: 10.1371/journal.pone.0021463. Francesca Soncin, Lisa Mohamet, Sarah Ritson, Kate Hawkins, Nicoletta Bobola, Leo Zeef, Catherine L. R.
Cell, 14 July 2011 Frank Soldner et al. “Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations.” A method
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