Exosomes are tiny vesicles released from cells that carry proteins, lipids, and nucleic acids: cargo that can affect the biology of recipient cells. In a
Researchers say that they have found a way to smuggle drug-carrying nanoparticles past the body’s immune system: by camouflaging them to look like cell fragments
Researchers say that they have found a way to smuggle drug-carrying nanoparticles past the body’s immune system: by camouflaging them to look like cell fragments
A protein embedded in the surface of mitochondria opens the door to apoptosis, causing cells to experience severe power failures, according to new work by
A possible approach for inducing cancer cells to revert to a precancerous state is based on the protein PLEKHA7 (Pleckstrin homology domain-containing family A member
Although recent studies have provided a wealth of information about archaeal biology, nothing is known about the molecular basis of DNA segregation in these organisms.
The types of lipids mice consume affect the composition of their gut microbiota, which influences whether the animals develop obesity-related inflammation, according to a study
Scientists at UC Davis have found that early exposure to inflammatory cytokines, such as interleukin 2, can stymie the activity of CD4 T cells, immune
The origins of new fat cells (adipocytes), which we humans must make throughout our lives, have not been clear. Rodent studies have produced conflicting results
The physiological differences between males and females go far beyond reproduction; they may even include how an animal processes pain, according to a study published
Identifying the molecular mechanisms that underlie aging and their pharmacological manipulation are key aims for improving lifelong human health. Here, we identify a critical role
The T790M mutation in EGFR accounts for approximately half of all lung cancer cases with acquired resistance to the current clinical EGFR tyrosine kinase inhibitors.
Different cell culture conditions can impact genetic changes in human embryonic stem cells (ESCs), and these changes could affect the cells’ clinical utility, according to
A multidisciplinary research team has discovered how cells know to rush to a wound and heal it opening the door to new treatments for diabetes,
A collaboration of scientists from across Europe has discovered a cellular pathway that could lead to the development of new therapeutic interventions to stop or
Transcription factors form multiprotein complexes that coordinate gene expression and regulate cellular responses (1). In cancer, aberrantly expressed transcription factors often alter gene expression programs,
A key aspect of cancer metastases is the tendency for specific cancer cells to home to defined subsets of secondary organs. Despite these known tendencies,
Tumor cells appear more likely to metastasize if they are studded with too much Frizzled2, a kind of cell receptor, along with Wnt5, a signaling
ELR (glutamic acid-leucine-arginine motif positive) CXC chemokines, which bind heparin and signal through the receptors CXCR1 and CXCR2 in humans and CXCR2 in mice, have a
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